Skin hydration imaging using a long-wavelength near-infrared digital camera
Skin hydration imaging using a long-wavelength near-infrared digital camera
复制标题
使用长波长近红外数码相机进行皮肤水合成像
DOI：
10.1117/12.432483
复制
发表时间：
2001
期刊：
影响因子：
2.9
通讯作者：
Shuliang L. Zhang
中科院分区：
文献类型：
--
作者：
E. M. Attas;Trevor B. Posthumus;B. Schattka;M. Sowa;H. Mantsch;Shuliang L. Zhang
皮肤保湿是皮肤健康的关键因素。水合测量可以提供皮肤状况的诊断信息，并可以指示皮肤屏障功能的完整性。近红外光谱通过在特定波长对组织反射率的影响来测量活组织的水分含量。成像具有重要的优势，可以显示水合程度作为位置的函数。短波长(650-1050 nm)近红外光谱反射成像以前曾在体内用于在严格控制的实验室条件下确定皮肤的相对水分含量。我们最近开发了一种新的光谱成像系统，可以在近红外(960到1700 nm)的长波长区域获取图像集，那里的水吸收带更强。LW-NIR系统在物镜前面使用了一个液晶可调滤光片，并结合了一个12位数码相机和一个320×240像素的砷化铟-镓阵列传感器。定制软件控制相机和可调滤镜，允许近乎实时地获取和显示图像集。使用长波成像系统、短波成像系统和非成像仪器在临床环境中测量前臂皮肤的水化程度。其中，LW-NIR系统在测量皮肤脱水方面似乎是最敏感的。
Skin hydration is a key factor in skin health. Hydration measurements can provide diagnostic information on the condition of skin and can indicate the integrity of the skin barrier function. Near-infrared spectroscopy measures the water content of living tissue by its effect on tissue reflectance at a particular wavelength. Imaging has the important advantage of showing the degree of hydration as a function of location. Short-wavelength (650-1050 nm) near infrared spectroscopic reflectance imaging has previously been used in-vivo to determine the relative water content of skin under carefully controlled laboratory conditions. We have recently developed a novel spectroscopic imaging system to acquire image sets in the long-wavelength region of the near infrared (960 to 1700 nm), where the water absorption bands are more intense. The LW-NIR systems uses a liquid- crystal tunable filter in front of the objective lens and incorporates a 12-bit digital camera with a 320-by-240-pixel indium-gallium arsenide array sensor. Custom software controls the camera and tunable filter, allowing image sets to be acquired and displayed in near-real time. Forearm skin hydration was measured in a clinical context using the long- wavelength imaging system, a short-wavelength imaging system, and non-imaging instrumentation. Among these, the LW-NIR system appears to be the most sensitive at measuring dehydration of skin.