Human exposure to methylmercury through rice intake in mercury mining areas, guizhou province, china
Human exposure to methylmercury through rice intake in mercury mining areas, guizhou province, china
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中国贵州省汞矿区人类通过摄入大米接触甲基汞。
DOI：
10.1021/es071948x
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发表时间：
2008-01-01
影响因子：
11.4
通讯作者：
Fu, Xuewu
中科院分区：
文献类型：
--
作者：
Feng, Xinbin;Li, Ping;Fu, Xuewu
由于几起广为人知的灾难，甲基汞(Me-Hg)的毒性已引起公众的广泛关注。Me-Hg具有剧毒，神经系统是人类的主要靶子组织。虽然一般人主要通过受污染的鱼类和海洋哺乳动物接触Me-Hg，但在汞矿区，长期的采矿活动会对当地环境造成严重的汞污染。万山汞矿区98人的研究表明，头发Me-Hg水平表明Me-Hg暴露。当地居民的主食大米也显示出较高的总汞(T-Hg)和Me-Hg水平。采自万山汞矿区3个村的大米样品中总汞的几何平均浓度为36.2(4.9~214.7)微克/公斤，Me汞的平均浓度为8.5(1.9~2 7.6)微克/公斤，显著高于参考区的平均7.0(3.2~15.1)微克/公斤和2.5(0.8~4.3)微克/公斤。在万山汞矿区采集的猪肉、蔬菜和饮用水样品中，总汞含量很高，但汞含量很低。估计的大米Me-Hg摄入量与头发Me-Hg水平之间的关系(r=0.65，p<；0.001)证实了高Me-Hg水平的大米确实是万山汞矿区当地居民Me-Hg暴露的主要途径。根据我们的研究，我们可以得出结论，人类通过食物消费接触Me-Hg的主要方式并不局限于鱼类，在某些情况下，中国矿区的人经常吃米饭。
The toxicity of methylmercury (Me-Hg) has caused widespread public human concern as a result of several widely publicized disasters. Me-Hg is highly toxic, and the nervous system is its principal target tissue for humans. Although the general population is primarily exposed to Me-Hg through contaminated fish and marine mammals, in Hg mining areas a long history of mining activities can produce serious Hg pollution to the local environment In a study of 98 persons from the Wanshan Hg mining area, hair Me-Hg levels indicated Me-Hg exposure. Rice, the staple food of the local inhabitants also showed high total Hg (T-Hg) and Me-Hg levels. The geometric mean concentration of T-Hg and mean concentration of Me-Hg in rice samples collected from 3 villages in Wanshan Hg mining area were 36.2 (ranging from 4.9 to 214.7), and 8.5 (ranging from 1.9 to 27.6) microg/kg, respectively, which were significantly elevated compared to the rice samples collected from a reference area, where the mean T-Hg and Me-Hg concentrations were 7.0 (3.2-15.1) and 2.5 (0.8-4.3) microg/kg, respectively. Pork meat, vegetable, and drinking water samples collected in Wanshan Hg mining area contained highly elevated T-Hg, but very low levels of Me-Hg. The relationships between the estimated rice Me-Hg intake and hair Me-Hg levels (r = 0.65, p < 0.001) confirmed rice with high Me-Hg levels indeed was the main route of Me-Hg exposure for the local residents in the Wanshan Hg mining area. From our study, we can conclude that the main human exposure to Me-Hg via food consumption is not restricted to fish, but in some cases in mining areas of China to frequent rice meals.