A new type D retrovirus isolated from macaques with an immunodeficiency syndrome.
A new type D retrovirus isolated from macaques with an immunodeficiency syndrome.
复制标题
从患有免疫缺陷综合症的猕猴中分离出一种新型 D 型逆转录病毒。
作者：
Daniel;N. King;Norman L. Letvin;Ronald D. Hunt;P. Sehgal;R. C. Desrosiers
最近被描述为获得性免疫缺陷综合征的猕猴表现出明显的T淋巴细胞功能缺陷，并死于机会性感染和淋巴增殖异常。在这里描述的研究中，从两只患有这种综合征的猕猴身上分离到一种新的D型逆转录病毒。这种病毒与梅森-辉瑞猴子病毒有关，但与梅森-辉瑞猴子病毒不同，梅森-辉瑞猴子病毒是一种D型逆转录病毒，以前从恒河猴(Macaca Mulatta)的乳腺肿瘤中分离出来。
Macaque monkeys with the recently described acquired immunodeficiency syndrome show a marked defect in T-lymphocyte function and die with opportunistic infections and lymphoproliferative abnormalities. In the study described here a new type D retrovirus was isolated from two Macaca cyclopis with this syndrome. This virus is related to, but distinct from, Mason-Pfizer monkey virus, a type D retrovirus previously isolated from a mammary tumor of a rhesus monkey (Macaca mulatta).