Computational fluid dynamic modelling of the effect of ventilation mode and tracheal tube position on air flow in the large airways

Computational fluid dynamic modelling of the effect of ventilation mode and tracheal tube position on air flow in the large airways
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DOI:
10.1111/anae.13003
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发表时间:
2015-05-01
期刊:
影响因子:
10.7
通讯作者:
Pourkashanian, M.
Pourkashanian, M.
中科院分区:
医学1区
文献类型:
--
作者:
Lumb, A. B.;Burns, A. D.;Pourkashanian, M.

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我们已经使用计算流体动力学模型来研究气管导管的尺寸和位置对大气道中的区域气体流动的影响。使用三维数学模型,我们模拟了有和没有气管导管的流动,复制了生理和人工呼吸。通过气管导管通气增加了流向左肺的比例,从无导管的39.5%增加到43.1- 47.2%,这取决于导管位置。通气模式和气管与隆突的距离对流量没有影响。管的侧向位移和偏转增加了对同侧肺的通气;例如,当向中心左侧偏转10度时,左肺的流量从43.8%增加到53.7%。由于气管导管相对于气管的小直径,气体以高速离开导管,使得局部通气可能受到导管位置和角度变化的影响。
We have used computational fluid dynamic modelling to study the effects of tracheal tube size and position on regional gas flow in the large airways. Using a three-dimensional mathematical model, we simulated flow with and without a tracheal tube, replicating both physiological and artificial breathing. Ventilation through a tracheal tube increased proportional flow to the left lung from 39.5% with no tube to 43.1-47.2%, depending on tube position. Ventilation mode and tube distance from the carina had no effect on flow. Lateral displacement and deflection of the tube increased ventilation to the ipsilateral lung; for example, when deflected 10 degrees to the left of centre, flow to the left lung increased from 43.8 to 53.7%. Because of the small diameter of a tracheal tube relative to the trachea, gas exits a tube at high velocity such that regional ventilation may be affected by changes in the position and angle of the tube.