Seborrheic keratosis that follows Blaschko's lines
Seborrheic keratosis that follows Blaschko's lines
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Blaschko 线型脂溢性角化病
DOI：
10.1111/j.1346-8138.2008.00471.x
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发表时间：
2008
期刊：
影响因子：
--
通讯作者：
A. Ozawa
中科院分区：
文献类型：
--
作者：
T. Mabuchi;E. Akasaka;Akio Kondoh;Y. Umezawa;T. Matsuyama;A. Ozawa
一例66岁日本男性躯干左侧和左上肢皮肤病变约10年。皮损无症状，但逐渐增大，将患者带到我院。首次检查时，我们发现胸部和腹部左侧以及左上肢有5 mm × 5 mm至15 mm × 5 mm的圆形或椭圆形浅至深棕色角化性丘疹。丘疹在躯干上排列成S形线，在上肢上排列成直线。临床和组织病理学结果导致了遵循Blaschko线的脂溢性角化病的诊断。据我们所知，以前没有报告过这种情况。我们的病例支持这一假设，即脂溢性角化病可以与遗传镶嵌。
A 66‐year‐old Japanese man had skin lesions on the left side of his trunk and the left upper extremity for approximately 10 years. The skin lesions were asymptomatic but increased gradually, which brought the patient to our hospital. On the initial examination, we noticed 5 mm × 5 mm to 15 mm × 5 mm, round or oval, light to dark brown keratotic papules on the left side of chest and abdomen and the left upper extremity. The papules were aligned in an S‐shaped line on the trunk and in a straight line on the upper extremity. Clinical and histopathological findings led to a diagnosis of seborrheic keratosis that followed Blaschko's lines. To our knowledge, no such a case has been reported previously. Our case supports the hypothesis that seborrheic keratosis can be associated with genetic mosaicism.