Ircinamine B, bioactive alkaloid from marine sponge Dactylia sp.

Ircinamine B, bioactive alkaloid from marine sponge Dactylia sp.
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DOI:
10.1016/j.tetlet.2006.09.020
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发表时间:
2006-11-06
影响因子:
1.8
通讯作者:
Ono, Noboru
Ono, Noboru
中科院分区:
化学4区
文献类型:
--
作者:
Sato, Seizo;Kuramoto, Makoto;Ono, Noboru

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从日本佐田角采集的海绵Dactylia sp.中分离到Ircinine B。在广泛光谱分析的基础上,确定了分离代谢物的结构。该化合物对小鼠白血病细胞株P388具有中等活性(IC50为0.28µg/mL)。(C)2006爱思唯尔有限公司。保留所有权利。
Ircinamine B was isolated from the marine sponge Dactylia sp., which was collected at Cape Sada in Japan. Based on extensive spectral analysis, the structures of the isolated metabolites were established. This novel compound showed moderate activity against the murine leukemia cell line P388 (IC50 0.28 mu g/mL). (c) 2006 Elsevier Ltd. All rights reserved.