Xenopus genomic data and browser resources.
Xenopus genomic data and browser resources.
复制标题
非洲爪蟾基因组数据和浏览器资源。
DOI：
10.1016/j.ydbio.2016.03.030
复制
发表时间：
2017
影响因子：
2.7
通讯作者：
Zorn,AaronM
中科院分区：
文献类型：
--
作者：
Vize,PeterD;Zorn,AaronM
生物医学研究中最常用的两种爪蟾是二倍体热带爪蟾和四倍体非洲爪蟾。The X。自2010年以来，Tropicalis基因组序列已经可用，今年X. laevis，来自两种不同遗传背景的基因组已经公布。可用于物种和转录组和表观遗传数据集的多基因组组装正在迅速增长，所有这些都可从各种网络资源获得。本文介绍了这些资源的内容，如何定位和下载基因组数据，以及如何在各种公共基因组浏览器上查看和操作这些数据，重点介绍了Xenbase，Xenopus模式生物数据库。
The two species ofXenopusmost commonly used in biomedical research are the diploidXenopus (Silurana) tropicalisand the tetraploidXenopus laevis. TheX. tropicalisgenome sequence has been available since 2010 and this year theX. laevis,genome from two distinct genetic backgrounds has been published. Multiple genome assemblies available for both species and transcriptomic and epigenetic data sets are growing rapidly, all of which are available from a variety of web resources. This review describes the contents of these resources, how to locate and download genomic data, and also how to view and manipulate these data on various public genome browsers, with an emphasis on Xenbase, theXenopusmodel organism database.