Protein sorting in complex plastids.
Protein sorting in complex plastids.
复制标题
复杂质体中的蛋白质分选。
DOI：
10.1016/j.bbamcr.2012.05.030
复制
发表时间：
2013
期刊：
影响因子：
--
通讯作者：
Striepen,Boris
中科院分区：
文献类型：
--
作者：
Sheiner,Lilach;Striepen,Boris
在内共生的 pivitol 事件中驯服蓝细菌，为真核生物带来了光合作用，并产生了在灰藻、红藻和绿藻以及后者的后代植物中发现的质体。过去二十年的超微结构和分子研究表明，质体在生命树上具有令人惊讶的横向移动性。许多独立的二级和三级内共生导致质体扩散到各种非光合作用谱系中。原生生物愉快地进食并随后相互驯化，征服了各种各样的生态位。次级质体或复杂质体的复杂进化反映在结合它们的众多膜上（与初级质体的两个膜相比，有三个或四个膜）。基因转移到宿主细胞核是内共生的标志，并提供集中的细胞控制。在这里，我们回顾了这些蛋白质如何返回细胞器基质，并描述了在理解允许蛋白质跨四膜易位的分子机制方面取得的进展。本文是题为“线粒体和质体中的蛋白质导入和质量控制”的特刊的一部分。
Taming a cyanobacterium in a pivitol event of endosymbiosis brought photosynthesis to eukaryotes, and gave rise to the plastids found in glaucophytes, red and green algae, and the descendants of the latter, the plants. Ultrastructural as well as molecular research over the last two decades has demonstrated that plastids have enjoyed surprising lateral mobility across the tree of life. Numerous independent secondary and tertiary endosymbiosis have led to a spread of plastids into a variety of, up to that point, non-photosynthetic lineages. Happily eating and subsequently domesticating one another protists conquered a wide variety of ecological niches. The elaborate evolution of secondary, or complex, plastids is reflected in the numerous membranes that bound them (three or four compared to the two membranes of the primary plastids). Gene transfer to the host nucleus is a hallmark of endosymbiosis and provides centralized cellular control. Here we review how these proteins find their way back into the stroma of the organelle and describe the advances in the understanding of the molecular mechanisms that allow protein translocation across four membranes. This article is part of a Special Issue entitled: Protein Import and Quality Control in Mitochondria and Plastids.