Tn1331, a novel multiresistance transposon encoding resistance to amikacin and ampicillin in Klebsiella pneumoniae

Tn1331, a novel multiresistance transposon encoding resistance to amikacin and ampicillin in Klebsiella pneumoniae
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DOI:
10.1128/aac.31.12.1955
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发表时间:
1987-12
影响因子:
4.9
通讯作者:
M. Tolmasky;J. H. Crosa
M. Tolmasky;J. H. Crosa
中科院分区:
医学2区
文献类型:
--
作者:
M. Tolmasky;J. H. Crosa

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A 7.5-kilobase-pair multiresistance transposon, Tn1331, harboring amikacin resistance was identified as part of Klebsiella pneumoniae plasmid pJHCMW1. Restriction mapping, hybridization, and transposition complementation experiments demonstrated that Tn1331 belongs to the Tn3 family. Its structure is similar to that of Tn3 with the insertion of a DNA fragment encoding resistance to amikacin, kanamycin, and tobramycin.