Case-control studies of cancer in New Zealand electrical workers.
Case-control studies of cancer in New Zealand electrical workers.
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新西兰电力工人癌症的病例对照研究。
DOI：
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发表时间：
1989
影响因子：
7.7
通讯作者：
James Fraser
中科院分区：
文献类型：
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作者：
Neil Pearce;John S. Reif;James Fraser
包括新西兰病例对照研究在内的一系列报告表明，电气工人患白血病的风险增加。我们在这里报告了基于新西兰癌症登记处的进一步一系列病例对照研究。这些研究涉及1980-1984年期间登记的19，904名男性癌症患者，登记时年龄在20岁或以上。对于每个癌症部位，其他部位的登记形成对照组。有三个主要发现。首先，新西兰电气工人患白血病的风险升高（比值比（OR）= 1.62，95%置信区间（CI）1.04-2.52），但几乎没有证据表明其他癌症部位的风险增加。其次，与其他已发表的研究相反，风险增加主要是慢性白血病（OR = 2.12）而不是急性白血病（OR = 1.25），淋巴白血病（OR = 1.73）而不是髓系白血病（OR = 1.22）。第三，某些类别的电气工作，包括收音机和电视修理工，（OR = 7.86，95%CI 2.20-28.09），电工（OR = 1.68，95% CI = 0.75-3.79）、线路工（OR = 2.35，95% CI 0.97-5.70）和电站操作工（OR = 3.89，95% CI 1.00-15.22）。
A series of reports, including a New Zealand case-control study, have suggested that electrical workers are at increased risk of leukaemia. We report here a further series of case-control studies based on the New Zealand Cancer Registry. These involved 19,904 male patients registered with cancer for the period 1980-1984 who were aged 20 years or more at time of registration. For each cancer site, the registrations for other sites formed the control group. Three main findings emerged. First, there is an elevated leukaemia risk in New Zealand electrical workers (odds ratio (OR) = 1.62, 95% confidence interval (Cl) 1.04-2.52), but little evidence of increased risks for other cancer sites. Second, contrary to other published studies, the increased risk was primarily for chronic leukaemia (OR = 2.12) rather than acute leukaemia (OR = 1.25), and for lymphatic leukaemia (OR = 1.73) rather than myeloid leukaemia (OR = 1.22). Third, the increased risk was strongest for certain categories of electrical work including radio and television repairers (OR = 7.86, 95% CI 2.20-28.09), electricians (OR = 1.68, 95% Cl = 0.75-3.79), linemen (OR = 2.35, 95% Cl 0.97-5.70) and power station operators (OR = 3.89, 95% Cl 1.00-15.22).