Gas-chromatographic analysis for cocaine in human plasma, with use of a nitrogen detector.
Gas-chromatographic analysis for cocaine in human plasma, with use of a nitrogen detector.
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使用氮气检测器对人血浆中的可卡因进行气相色谱分析。
作者：
P. Jatlow;D. Bailey
我们描述了一种用氮检测器用气相色谱测定血浆中可卡因浓度的方法。该程序在接受鼻内可卡因表面麻醉的患者身上进行了测试。以苯甲酰ecGonine的丙酯为内标。该方法的灵敏度下限为每升血浆5-10杯可卡因。浓度为50和100µg/L时，变异系数分别为5.3%和3.0%。
We describe a procedure for measuring the concentration of cocaine in plasma by gas chromatography, with use of a nitrogen detector. The procedure was tested on patients receiving intranasal cocaine for topical anesthesia. The propyl ester of benzoylecgonine is used as an internal standard. The lower limit of sensitivity of the procedure is 5--10 mug of cocaine per liter of plasma. The coefficients of variation are 5.3% and 3.0% for concentrations of 50 and 100 mug/liter, respectively.