Pd-catalyzed cyclization of 1-allyl-2-indolecarboxamides by intramolecular amidation of unactivated ethylenic bond
Pd-catalyzed cyclization of 1-allyl-2-indolecarboxamides by intramolecular amidation of unactivated ethylenic bond
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DOI：
10.1055/s-2005-922788
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发表时间：
2006-01-05
期刊：
影响因子：
2
通讯作者：
Paladino, G
中科院分区：
文献类型：
--
作者：
Abbiati, G;Beccalli, E;Paladino, G
分子内Pd(II)介导的1-烯丙基-2-吲哚甲酰胺的环化反应导致吡嗪并[1，2-a]吲哚与酰胺基反应，将烯烃的C-H键转化为C-N键。当作用于烯丙基酰胺时，观察到具有双C-H官能化的多米诺骨牌过程。
The intramolecular Pd(II)-mediated cyclization of 1-allyl-2-indolecarboxamides leads to pyrazino[1,2-a]indoles throng the conversion of the olefinic C-H bond into a C-N bond by reaction with an amide group. When operating on the allylamide, a domino process was observed with a double C-H functionalization.