Neurons in cat lateral geniculate nucleus that concentrate exogenous [3H]-gamma-aminobutyric acid (GABA).

Neurons in cat lateral geniculate nucleus that concentrate exogenous [3H]-gamma-aminobutyric acid (GABA).
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猫外侧膝状体核中浓缩外源性 [3H]-γ-氨基丁酸 (GABA) 的神经元。

DOI:
10.1002/cne.901920408
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发表时间:
1980
期刊:
The Journal of comparative neurology
影响因子:
--
通讯作者:
Davis,TL
Davis,TL
中科院分区:
--
文献类型:
--
作者:
Sterling,P;Davis,TL

文献摘要

被引文献

相似文献

猫外侧膝状体A层中约四分之一的神经元选择性地积累外源性[3 H]-γ-氨基丁酸(GABA)、其类似物[3 H]-2,4-二氨基丁酸(DABA)和GABA激动剂[3 H]蝇蕈醇。这些神经元很小(直径12-18 μm),缺乏层状体,这表明它们对应于高尔基体中鉴定的III类细胞。GABA和DABA也通过F-末端积累,其在视网膜末端的突触后和中继细胞树突的突触前。这表明GABA可能是这些小神经元的递质,这些小神经元似乎通过局部回路介导了对中继细胞的前馈抑制。
About one‐quarter of the neurons in the A‐laminae of the cat lateral geniculate selectively accumulate exogenous [3H]‐γ‐aminobutyric acid (GABA), its analog, [3H]‐2,4‐diaminobutyric acid (DABA), and the GABA agonist, [3H] muscimol. These neurons are small (12–18 μm diameter) and lack a laminar body, which suggests that they correspond to the class III cell identified in Golgi material. GABA and DABA are also accumulated by F‐terminals which are post‐synaptic to retinal terminals and presynaptic to relay cell dendrites. It is suggested that GABA may be the transmitter for these small neurons which appear to mediate by means of local circuits a feed‐forward inhibition onto the relay cells.