Irregular Shape of Intracranial Aneurysm Indicates Rupture Risk Irrespective of Size in a Population-Based Cohort
Irregular Shape of Intracranial Aneurysm Indicates Rupture Risk Irrespective of Size in a Population-Based Cohort
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DOI：
10.1161/strokeaha.115.012404
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发表时间：
2016-05-01
期刊：
影响因子：
8.3
通讯作者：
Frosen, Juhana
中科院分区：
文献类型：
--
作者：
Lindgren, Antti E.;Koivisto, Timo;Frosen, Juhana
背景和目的-囊状颅内动脉瘤（sIA）的大小和形状反映了sIA壁的状况，并且是先前随访研究中破裂的风险因素。我们研究了如何以及大小或形状识别破裂倾向sIAs.Methods-In人口为基础的登记，我们调查了破裂的sIAs在一个单一的神经外科中心（1980-2014）的特点。除单因素分析外，多因素分析中还采用了逻辑回归，并采用受试者工作特征曲线计算了大小或形状的敏感性和特异性。
Background and Purpose-Size and shape of saccular intracranial aneurysms (sIA) reflect the condition of the sIA wall and were risk factors for rupture in previous follow-up studies. We investigated how well size or shape identify rupture-prone sIAs.Methods-In a population-based registry, we investigated the characteristics of ruptured sIAs treated in a single neurosurgical center (1980-2014). In addition to univariate analysis, logistic regression was used in multivariate analysis, and sensitivity and specificity of size or shape were calculated using receiver operating characteristic curves.Results-Ruptured sIAs were on average larger than unruptured sIAs (median, 7 versus 4 mm; P