Effects of pressure on fast axoplasmic flow. An in vitro study in the vagus nerve of rabbits.
Effects of pressure on fast axoplasmic flow. An in vitro study in the vagus nerve of rabbits.
复制标题
压力对快速轴浆流的影响。
DOI：
--
复制
发表时间：
1978
期刊：
影响因子：
--
通讯作者：
Rudolph W. Hahnenberger
中科院分区：
文献类型：
--
作者：
Rudolph W. Hahnenberger
通过使用径向的液体流，可以在体外用已知的压力压迫一段神经，而不会中断神经的氧气和营养物质的供应。室温下用~3H-亮氨酸标记兔迷走神经运动神经元。当神经受到20毫米汞柱压力时，快速轴浆流量没有改变，但在30毫米汞柱时有轻微但持续的抑制，在60毫米汞柱和90毫米汞柱时更加明显。加压60 mm Hg4 h时，压力引起的轴浆血流阻断是可逆的，而压迫神经15 h时，仅5例可逆性。
By using a radially directed stream of fluid it is possible to compress a section of a nerve in vitro by known pressures without interrupting the supply of oxygen and nutrients to the nerve. Motor neurons of the vagus nerves of rabbits labelled with 3H-leucine were used at room temperature. When a nerve was subjected to 20 mmHg pressure fast axoplasmic flow was not altered, but at 30 mmHg there was a slight but consistent inhibition, which was even more marked at 60 mmHg and still more at 90 mmHg. The pressure induced block of axoplasmic flow was reversible when 60 mmHg pressure was applied for as long as 4 h, when the nerves were compressed for 15 h there was reversibility in only 5 out of 8 cases.