Polysomnographic and Subjective Profiles of Sleep Continuity Before and After Mindfulness-Based Cognitive Therapy in Partially Remitted Depression
Polysomnographic and Subjective Profiles of Sleep Continuity Before and After Mindfulness-Based Cognitive Therapy in Partially Remitted Depression
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DOI：
10.1097/psy.0b013e3181dc1bad
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发表时间：
2010-07-01
影响因子：
3.3
通讯作者：
Bootzin, Richard R.
中科院分区：
文献类型：
--
作者：
Britton, Willoughby B.;Haynes, Patricia L.;Bootzin, Richard R.
目的：在一项随机对照试验中，探讨正念冥想 (MM) 是否与客观测量的多导睡眠图 (PSG) 睡眠状况的变化相关，并将 PSG 睡眠的变化与主观报告的睡眠和抑郁变化联系起来。先前的研究表明，正念和其他形式的冥想训练与睡眠质量的改善有关。然而，这些研究均未在首次受试者的纵向随机对照试验中使用客观 PSG 睡眠记录。方法：26 名部分缓解抑郁症的患者被随机分配到为期 8 周的基于正念的认知治疗 (MBCT) 课程或候补对照条件组。前后测量包括 PSG 睡眠研究以及主观报告的睡眠和抑郁症状。结果：根据 PSG 睡眠，MM 练习与皮质唤醒的多个指标相关，包括相对于对照组更多的觉醒和第一阶段睡眠以及更少的慢波睡眠，与 MM 练习的量成比例。根据睡眠日记，主观报告的睡眠在 MBCT 后有所改善，但并未超出对照。 MBCT 组的贝克抑郁量表评分比对照组下降更多。抑郁症的改善与主观睡眠连续性的增加和 PSG 唤醒的增加有关。结论：MM 与睡眠期间客观测量的觉醒程度的增加有关，同时主观报告的睡眠质量和情绪障碍也有所改善。这种模式类似于常见抗抑郁药物的阳性反应者的情况。
Objectives: To examine whether mindfulness meditation (MM) was associated with changes in objectively measured polysomnographic (PSG) sleep profiles and to relate changes in PSG sleep to subjectively reported changes in sleep and depression within the context of a randomized controlled trial. Previous studies have indicated that mindfulness and other forms of meditation training are associated with improvements in sleep quality. However, none of these studies used objective PSG sleep recordings within longitudinal randomized controlled trials of naive subjects. Methods: Twenty-six individuals with partially remitted depression were randomized into an 8-week Mindfulness-Based Cognitive Therapy (MBCT) course or a waitlist control condition. Pre-post measurements included PSG sleep studies and subjectively reported sleep and depression symptoms. Results: According to PSG sleep, MM practice was associated with several indices of increased cortical arousal, including more awakenings and stage 1 sleep and less slow-wave sleep relative to controls, in proportion to amount of MM practice. According to sleep diaries, subjectively reported sleep improved post MBCT but not above and beyond controls. Beck Depression Inventory scores decreased more in the MBCT group than controls. Improvements in depression were associated with increased subjective sleep continuity and increased PSG arousal. Conclusions: MM is associated with increases in objectively measured arousal during sleep with simultaneous improvements in subjectively reported sleep quality and mood disturbance. This pattern is similar to the profiles of positive responders to common antidepressant medications.