The association between exposure to second-hand smoke and major depressive disorder in perimenopausal women: results from apopulation-based study
The association between exposure to second-hand smoke and major depressive disorder in perimenopausal women: results from apopulation-based study
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DOI：
10.1080/07853890.2018.1534264
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发表时间：
2018-01-01
影响因子：
4.4
通讯作者：
Chu, Chun-Lin
中科院分区：
文献类型：
--
作者：
Chen, Ching-Yen;Chang, Chia-Ming;Chu, Chun-Lin
目的：本研究的目的是检验暴露于二手烟（SHS）与重度抑郁症（MDD）在围绝经期妇女中正相关的假设，从基于人群的角度，调整所有潜在的混杂因素后。方法：本研究使用国家健康和营养调查（NHANES）数据库，2005-2012年，报告围绝经期妇女的MDD。与家中没有吸烟者相比，家中有吸烟者时MDD的比值比（OR）增加（aOR=2.97，95%置信区间[CI]=1.15-7.67）;然而，在非贫困组中，家中有或没有吸烟者的MDD的OR没有差异。对于那些自我评价他们的健康状况为优秀，非常好或良好的参与者，MDD的OR增加;如果家中有吸烟者，与家中没有吸烟者的参与者相比，MDD的OR也会增加（aOR=2.58，95%CI =1.08-6.14）。目前的研究结果增加了我们对SHS的临床和公共卫生意义的理解，以及各种社会经济和自我评价的健康状况的作用，围绝经期妇女。
Purpose: The aim of this study was to test the hypothesis that exposure to second-hand smoke (SHS) would be positively associated with major depressive disorder (MDD) in perimenopausal women from a population-based perspective, after adjustment for all potential confounders.Methods: This study used the National Health and Nutrition Examination Survey (NHANES) database, 2005-2012, to report on MDD in perimenopausal women.Results: The odds ratio (OR) for MDD increased when there was a smoker was in the home, as compared to not having a smoker in the home (aOR=2.97, 95% confidence interval [CI]=1.15-7.67); however, in the non-poor group, the OR for MDD showed no difference between those who had or did not have a smoker in their home. For participants who self-rated their health condition as excellent, very good or good, the OR for MDD increased; it also increased if there were smokers in the home, as compared to those without smokers in the home (aOR=2.58, 95% CI=1.08-6.14).Conclusions: The present study results augment our understanding of the clinical and public health significance of SHS, as well as the role of various socioeconomic and self-rated health conditions, in perimenopausal women.