Changes in skeletal muscle in males and females following endurance training
Changes in skeletal muscle in males and females following endurance training
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DOI：
10.1139/cjpp-79-5-386
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发表时间：
2001-05-01
影响因子：
2.1
通讯作者：
Tarnopolsky, MA
中科院分区：
文献类型：
--
作者：
Carter, SL;Rennie, CD;Tarnopolsky, MA
耐力运动中底物选择的性别差异有报道。到目前为止，还没有研究关注男女耐力运动训练后肌肉酶的适应情况。我们研究了7周耐力运动训练计划对雄性和雌性β -氧化、三羧酸循环和电子传递链酶活性以及纤维类型分布的影响。训练导致男性和女性的(V)超过点O-2峰值分别增加17%和22% （P < 0.001）。以下肌肉酶活性在两性中均有相似的增加：3- β -羟酰基辅酶a脱氢酶（38%）、柠檬酸合成酶（41%）、琥珀酸-细胞色素c氧化还原酶（41%）和细胞色素c氧化酶（COX; 26%）。COX活性的升高与(V) over dot o -2峰值/无脂质量的升高呈显著相关（R-2 = 0.52, P < 0.05）。纤维面积、大小和%面积不受训练的影响，但男性的II型纤维面积较大（P < 0.05），女性的I型纤维%面积较大（P < 0.05）。耐力训练对男性和女性骨骼肌氧化电位的影响相似。训练对男女的纤维类型分布和大小没有影响。
Gender differences in substrate selection have been reported during endurance exercise. To date, no studies have looked at muscle enzyme adaptations following endurance exercise training in both genders. We investigated the effect of a 7-week endurance exercise training program on the activity of beta-oxidation, tricarboxylic acid cycle and electron transport chain enzymes, and fiber type distribution in males and females. Training resulted in an increase in (V) over dot O-2 peak for both males and females of 17% and 22%, respectively (P < 0.001). The following muscle enzyme activities increased similarly in both genders: 3-beta -hydroxyacyl CoA dehydrogenase (38%), citrate synthase (41%), succinate-cytochrome c oxidoreductase (41%), and cytochrome c oxidase (COX; 26%). The increase in COX activity was correlated (R-2 = 0.52, P < 0.05) with the increase in (V) over dot O-2peak/ fat free mass. Fiber area, size, and % area were not affected by training for either gender, however, males had larger Type II fibers (P < 0.05) and females had a greater Type I fiber % area (P < 0.05). Endurance training resulted in similar increases in skeletal muscle oxidative potential for both males and females. Training did not affect fiber type distribution or size in either gender.