Pharyngeal gonorrhea in female sex workers: Response to a single 2-g dose of azithromycin
Pharyngeal gonorrhea in female sex workers: Response to a single 2-g dose of azithromycin
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DOI：
10.1097/01.olq.0000204675.92459.3c
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发表时间：
2006-08-01
影响因子：
3.1
通讯作者：
Shohat, Tamy
中科院分区：
文献类型：
--
作者：
Dan, Michael;Poch, Francesca;Shohat, Tamy
目的：自1999年以来，以色列特拉维夫的淋病发病率急剧上升。几乎一半的受访患者承认从性工作者那里感染。在三分之二的病例中，口交（口交）是最有可能感染该疾病的途径。在目前的研究中，我们评估了在特拉维夫的性工作者之间的咽部淋病的患病率，并评估了一个单一的2克剂量的阿奇霉素在根除infection.Methods的有效性：从301女性性工作者在妓院执业的淋球菌培养的咽喉标本。对所有参与者进行了一份涵盖人口统计学和性行为信息的问卷调查，并在监督下口服单次2 g剂量。培养阳性的妇女一周后复查淋病奈瑟菌根除。结果：淋病奈瑟菌分离出27名妇女（9%）。咽部淋病女性的中位年龄为23岁（范围，18-32岁）; 85%出生在前苏联（主要是俄罗斯，乌克兰，摩尔达维亚）。据报道，88%的参与者在阴道性交时定期使用避孕套，而只有60%的参与者在口交时总是使用避孕套。所有分离株对阿奇霉素均敏感（MIC
Objectives: A sharp increase in the incidence of gonorrhea has been observed in Tel Aviv, Israel, since 1999. Almost one half of interviewed patients admitted contracting the infection from a sex worker. In two thirds of the cases, oral sex (fellatio) was the most probable route of acquiring the disease. In the current study, we assessed the prevalence of pharyngeal gonorrhea among sex workers in Tel Aviv and evaluated the efficacy of a single 2-g dose of azithromycin in eradicating the infection.Methods: Throat specimens were obtained for gonococcal culture from 301 female sex workers practicing in brothels. A questionnaire covering demographic and sexual behavior information was administered to all participants, and a single 2-g dose was administered orally under supervision. Women with positive cultures were reexamined a week later for eradication of Neisseria gonorrhoeae.Results: N gonorrhoeae was isolated from 27 women (9%). The median age of women with pharyngeal gonorrhea was 23 years (range, 18-32 years); 85% were born in former Soviet Union (mostly Russia, Ukraine, Moldavia). Regular condom use in vaginal sex was reported by 88 % of the participants, whereas only 60 % reported always using condoms in oral sex. All isolates were susceptible to azithromycin (MIC