Silicon Nanowire-Based Fluorescent Nanosensor for Complexed Cu2+ and its Bioapplications
Silicon Nanowire-Based Fluorescent Nanosensor for Complexed Cu2+ and its Bioapplications
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基于硅纳米线的复合 Cu2 荧光纳米传感器及其生物应用
DOI：
10.1021/nl500276x
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发表时间：
2014-06-01
期刊：
影响因子：
10.8
通讯作者：
Shi, Wensheng
中科院分区：
文献类型：
--
作者：
Miao, Rong;Mu, Lixuan;Shi, Wensheng
实现了基于硅纳米线(SiNWs)的络合Cu2+荧光传感器。本传感器的高灵敏度和高选择性为其在生物领域的应用提供了便利。该传感器已成功应用于肝脏提取液中Cu2+的检测。同时，利用所制备的基于SiNW阵列的传感器对凋亡的HeLa细胞中Cu2+的释放进行了实时和原位监测。这些结果表明，基于SiNWs的传感器在揭示Cu2+的生理和病理作用方面具有潜在的应用价值。
A silicon nanowires (SiNWs)-based fluorescent sensor for complexed Cu2+ was realized. High sensitivity and selectivity of the present sensor facilitate its bioapplications. The sensor was successfully used to detect the Cu2+ in liver extract. Meanwhile, real-time and in situ monitoring of Cu2+ released from apoptotic HeLa cell was performed using the as-prepared SiNW arrays-based sensor. These results indicate that the present SiNWs-based sensor would be of potential applications in revealing the physiological and pathological roles of Cu2+.