Bipolar spectrum traits and the space between Madness and Genius: The Muse is in the Dose.
Bipolar spectrum traits and the space between Madness and Genius: The Muse is in the Dose.
复制标题
双极谱特征以及疯狂与天才之间的空间：缪斯就在剂量中。
DOI：
10.1016/j.jpsychires.2022.07.009
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发表时间：
2022
影响因子：
4.8
通讯作者：
Kelsoe,JohnR
中科院分区：
文献类型：
--
作者：
Greenwood,TiffanyA;Chow,LaurenJ;Gur,RubenC;Kelsoe,JohnR
创造力长期以来一直与双相谱系有关，特别是在未受影响的一级亲属和那些双相特征表现较温和的人中，这表明双相谱系的某些方面可能赋予创造力优势。在这里，我们采取了多方面的方法来更好地定义创造力和双相情感障碍之间的共同脆弱性。我们招募了135名双相情感障碍患者，102名创造性对照，103名非创造性对照，共340名参与者。所有参与者都完成了一项综合评估，其中包括几份自我报告的气质和个性问卷，一项跨多个领域的认知功能计算机测试，以及对创造性表现和成就的评估。显著的组间差异被观察到的假设共享的脆弱性特征轻躁狂人格，循环型气质，冲动，积极的神经质。虽然创造性和双极组都表现出上级创造能力，但只有创造性组表现出更好的认知表现。考虑到特质之间的相互关系，开放性、轻躁狂人格、发散性思维和推理能力的组合成为创造力的最强预测因子，共同解释了创造性成就34%的方差，并正确分类了85%的具有高成就的个体，无论诊断如何。这些结果证实并扩展了早期的观察创造力和双相情感障碍之间的共同脆弱性，并表明轻度至中度的双相频谱特征的表达与增强的认知功能和创造性表达相关。需要对这些特征进行进一步的研究，以澄清这种共同的脆弱性的性质，并提出个性化的治疗策略，以改善双相情感障碍的临床结局。
Creativity has long been associated with the bipolar spectrum, particularly among unaffected first-degree relatives and those with milder expressions of bipolar traits, suggesting that some aspects of the bipolar spectrum may confer advantages for creativity. Here we took a multifaceted approach to better define the shared vulnerability between creativity and bipolar disorder. We recruited 135 individuals with bipolar disorder, 102 creative controls, and 103 non-creative controls for a total of 340 participants. All participants completed a comprehensive assessment battery that included several self-report temperament and personality questionnaires, a computerized test of cognitive function across multiple domains, and an evaluation of creative performance and achievement. Significant group differences were observed for the hypothesized shared vulnerability traits of hypomanic personality, cyclothymic temperament, impulsivity, and positive schizotypy. While both the creative and bipolar groups demonstrated superior creative ability, the creative group alone revealed enhanced cognitive performance. Accounting for intercorrelations between traits, a combination of openness, hypomanic personality, divergent thinking, and reasoning ability emerged as the strongest predictors of creativity, collectively explaining 34% of the variance in creative achievement and correctly classifying 85% of individuals with high achievement irrespective of diagnosis. These results confirm and extend earlier observations of a shared vulnerability between creativity and bipolar disorder and suggest that mild to moderate expressions of bipolar spectrum traits are associated with enhanced cognitive functioning and creative expression. Further investigation of these traits is needed to clarify the nature of this shared vulnerability and suggest individualized treatment strategies to improve clinical outcomes in bipolar disorder.