Who is "Molly'? MDMA adulterants by product name and the impact of harm-reduction services at raves
Who is "Molly'? MDMA adulterants by product name and the impact of harm-reduction services at raves
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DOI：
10.1177/0269881117715596
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发表时间：
2017-08-01
影响因子：
4.1
通讯作者：
Johnson, Matthew W.
中科院分区：
文献类型：
--
作者：
Saleemi, Sarah;Pennybaker, Steven J.;Johnson, Matthew W.
亚甲二氧基甲基苯丙胺（MDMA），通常以“摇头丸”或“莫莉”的名义出售，通常用于音乐节，据报道，在过去十年中，死亡人数增加。摇头丸经常掺假，含有增加发病率和死亡率的化合物。虽然用户和临床医生通常认为以Molly销售的产品是掺假较少的MDMA产品，但这尚未经过测试。此外，虽然有时在狂欢派对上提供药丸测试服务，但这些服务减少危险药物使用的假设尚未得到研究。这项研究分析了药物测试组织DanceSafe从2010年至2015年美国各地事件中收集的数据。在收集的529份样本中，比色试剂检测仅在60%的样本中发现了摇头丸。在Eccident和Molly之间，MDMA检测阳性的样本百分比没有显著差异。如果测试未发现MDMA，则个人报告使用产品的意图的可能性显著降低（相对风险（RR）= 0.56，p = 0.01）。结果表明，莫莉不是一种掺假较少的物质，药丸测试服务是一种合法的减少伤害的服务，减少了消费潜在危险物质的意图，可能需要立法者考虑法律的保护。未来的研究应进一步检查药丸测试服务的直接影响，并包括更广泛的药丸测试方法。
Methylenedioxymethamphetamine (MDMA), often sold as Ecstasy' or Molly', is commonly used at music festivals and reported to be responsible for an increase in deaths over the last decade. Ecstasy is often adulterated and contains compounds that increase morbidity and mortality. While users and clinicians commonly assume that products sold as Molly are less-adulterated MDMA products, this has not been tested. Additionally, while pill-testing services are sometimes available at raves, the assumption that these services decrease risky drug use has not been studied. This study analyzed data collected by the pill-testing organization, DanceSafe, from events across the United States from 2010 to 2015. Colorimetric reagent assays identified MDMA in only 60% of the 529 samples collected. No significant difference in the percentage of samples testing positive for MDMA was determined between Ecstasy and Molly. Individuals were significantly less likely to report intent to use a product if testing did not identify MDMA (relative risk (RR) = 0.56, p = 0.01). Results suggest that Molly is not a less-adulterated substance, and that pill-testing services are a legitimate harm-reduction service that decreases intent to consume potentially dangerous substances and may warrant consideration by legislators for legal protection. Future research should further examine the direct effects of pill-testing services and include more extensive pill-testing methods.