Hair Follicle‐like Change Over Histiocytomas
Hair Follicle‐like Change Over Histiocytomas
复制标题
组织细胞瘤的毛囊样改变
DOI：
10.1097/00000372-198612000-00002
复制
发表时间：
1986
期刊：
影响因子：
--
通讯作者：
R. Marks
中科院分区：
文献类型：
--
作者：
K. Dalziel;R. Marks
表皮增生是组织细胞瘤的常见表现。偶尔会出现一种特殊类型的基底细胞增生，分化为原始毛囊组织。本研究试图描述这种变化，并确定它是否与任何特定的临床或组织学特征有关。组织细胞瘤患者的数据显示病变上方表皮的柱状上皮诱导，与未显示这种变化的对照组的数据进行了比较。两组组织细胞瘤的大小、部位和持续时间相似，主要细胞类型和组织细胞瘤离表皮的距离也相似。组织细胞瘤的连续切片显示，柱状上皮的诱导是一种局灶性现象，在常规切片中经常被遗漏。这表明组织细胞瘤细胞可能产生一种“毛发组织介质”。
Epidermal hyperplasia is a common finding overlying histiocytomas. Occasionally, a distinctive type of basaloid hyperplasia occurs, with differentiation into primitive hair follicle tissue. This study attempts to characterize this change and determine whether it is associated with any particular clinical or histological feature. Data from patients with histiocytomas displaying induction of pilar epithelium in the epidermis above the lesions was compared with data from controls who did not show this change. The size, site, and duration of histiocytomas were similar in both groups, as were the predominant cell type and distance of histiocytoma from the epidermis. Serial sectioning of histiocytomas showed that the induction of pilar epithelium was a focal phenomenon, often missed in routine sections. It is suggested that histiocytoma cells may produce a “hair organizing mediator.”