AN AMPEROMETRIC ENZYME ELECTRODE FOR MONITORING BRAIN GLUCOSE IN THE FREELY MOVING RAT

AN AMPEROMETRIC ENZYME ELECTRODE FOR MONITORING BRAIN GLUCOSE IN THE FREELY MOVING RAT
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DOI:
10.1016/0304-3940(86)90527-6
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发表时间:
1986-12-23
影响因子:
2.5
通讯作者:
BARTLETT, PN
BARTLETT, PN
中科院分区:
医学4区
文献类型:
--
作者:
BOUTELLE, MG;STANFORD, C;BARTLETT, PN

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使用不可逆地吸附到有机导电盐上的葡萄糖氧化酶(EC1.1.3.4),用安培酶电极测量脑葡萄糖浓度。描述了电极的响应及其在体外和体内的稳定性。报告了注射胰岛素后脑葡萄糖和血糖(在植入的心房内插管样本中测量)的平行变化。
Brain glucose concentration was measured with an amperometric enzyme electrode using glucose oxidase (EC 1.1.3.4) irreversibly adsorbed onto an organic conducting salt. The responses of the electrode and its stability both in vitro and in vivo are described. Parallel changes in brain glucose and blood glucose (measured in samples from an implanted intra-atrial cannula) following injections of insulin are reported.