Tuberculosis infection among young adults enlisting in the United States Navy

Tuberculosis infection among young adults enlisting in the United States Navy
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DOI:
10.1093/ije/31.5.934
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发表时间:
2002-10-01
影响因子:
7.7
通讯作者:
Trump, DH
Trump, DH
中科院分区:
医学1区
文献类型:
--
作者:
Smith, B;Ryan, MAK;Trump, DH

文献摘要

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背景结核病(TB)是一种重新出现的全球性传染病威胁。为了保护美国军事人员的健康和准备,政策存在筛查和治疗潜在的结核病感染时,服务入口。方法采用多元回归分析方法,对1997年10月1日至1998年9月30日美国海军入伍的44128名青年进行结核病筛查,并对筛查结果进行统计学分析(年龄17-35岁,81%为男性)在这12个月期间接受结核病筛查。结核病潜伏感染率为3.5%。出生地与结核病感染密切相关,外国出生的新兵有反应性结核菌素皮肤试验或感染史的可能性高出8倍。那些谁报告他们的种族为“亚洲/太平洋岛屿”有证据表明结核病感染的几率是3.8倍相比,“高加索”新兵,即使调整后的出生地.Conclusions结核病感染的患病率在海军新兵中最后一次报告为2.5%,近10年前。这一大型队列中明显增加至3.5%可能是由于外国出生的新兵人数同时增加,它强调了在这一人群中全面筛查和治疗潜伏性结核感染的重要性。
Background Tuberculosis (TB) is a re-emerging infectious disease threat worldwide. To protect the health and readiness of US military personnel, policies exist to screen for and treat latent TB infection at the time of service entrance. Results of this screening programme have not been recently described.Methods Multivariate regression techniques were used to evaluate demographic and medical data associated with TB infection among all young adults entering US Navy enlisted service between 1 October 1997 and 30 September 1998.Results A total of 44 128 adults (ages 17-35, 81% male) were screened for TB during this 12-month period. The prevalence of latent TB infection was 3.5%. Place of birth was very strongly associated with TB infection, with foreign-born recruits eight times more likely to have a reactive tuberculin skin test or history of infection. Those who reported their race as 'Asian/Pacific Island' had 3.8 times the odds of having evidence of TB infection compared with 'Caucasian' recruits, even after adjusting for place of birth.Conclusions The prevalence of TB infection among Navy recruits was last reported as 2.5% nearly 10 years ago. The apparent increase to 3.5% in this large cohort is likely due to a concurrent increase in the number of foreign-born recruits, and it serves to underscore the importance of comprehensive screening and treatment of latent TB infections in this population.