Incidence and characterization of diarrheal enterotoxins of fecal Bacillus cereus isolates associated with diarrhea
Incidence and characterization of diarrheal enterotoxins of fecal Bacillus cereus isolates associated with diarrhea
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DOI：
10.1016/j.diagmicrobio.2007.06.014
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发表时间：
2007-12-01
影响因子：
2.9
通讯作者：
Shehabi, Asem A.
中科院分区：
文献类型：
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作者：
Al-Khatib, Mariam Saleh;Khyami-Horani, Hala;Shehabi, Asem A.
对490例腹泻患者和健康对照的粪便标本进行蜡样芽孢杆菌及其肠毒素的检测。有腹泻者的粪便中蜡样芽孢杆菌的发生率高于无腹泻者(9.5%比1.8%，P<；0.05)，1岁以下的人和1岁的成年人的粪便中蜡样双胞菌的发生率也高于1岁儿童(11%和8%比7.8%，P<；0.05)。蜡样芽孢杆菌溶血性肠毒素HBL基因(hblA、hblC、hblD)的阳性率分别为58%、58%、68%，而非溶血性肠毒素NHE基因(nheA、nheB、nheC)的阳性率分别为71.1%、84%、90%。本研究提示，携带一种或一种以上肠毒素基因的蜡样芽胞杆菌分离株(S)可能是约旦人群腹泻的潜在原因。(C)2007 Elsevier Inc.保留所有权利。
A total of 490 stool specimens were collected from patients with diarrhea and healthy controls without diarrhea to investigate the incidence of Bacillus cereus and its enterotoxins. B. cereus was found more significant in stools of persons with diarrhea than without diarrhea (9.5% versus 1.8%, P < 0.05), and was also detected more frequent but not significant in individuals aged >= 1 year and in adults than in children aged < 1 year (11% and 8% versus 7.8%, P > 0.05). The hemolytic enterotoxin HBL genes of B. cereus isolates (hblA, hblC, hblD) were detected in 58%, 58%, and 68%, respectively, whereas the nonhemolytic enterotoxin NHE genes (nheA, nheB, nheC) were detected more frequent in 71.%, 84%, and 90% of the isolates, respectively. This study suggests that B. cereus isolates harboring 1 or more enterotoxin gene(s) can be a potential cause of diarrhea in Jordanian population. (c) 2007 Elsevier Inc. All rights reserved.