The role of dietary fiber in regulating lipid bioaccessibility of almonds during mastication
The role of dietary fiber in regulating lipid bioaccessibility of almonds during mastication
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膳食纤维在调节杏仁咀嚼过程中脂质生物可及性中的作用
DOI：
10.1096/fasebj.26.1_supplement.1015.4
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发表时间：
2012
期刊：
影响因子：
--
通讯作者：
Ellis P
中科院分区：
文献类型：
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作者：
Ellis P
杏仁含有植物化学物质和营养素，可能对心脏病、糖尿病和肥胖症产生积极的健康益处。与这些益处相关的一个重要机制是咀嚼和消化过程中杏仁组织中脂质的生物可利用性（释放）。事实上，据报道，在富含杏仁饮食的人类受试者中，很大一部分脂质仍未消化，这主要是由于完整的细胞壁（膳食纤维）截留脂质造成的。然而，杏仁脂质的生物可利用性尚未量化。我们通过对健康人类志愿者（n = 15）进行咀嚼试验来研究这一点。使用机械筛分和激光衍射方法测量咀嚼杏仁的粒度分布。使用基于咀嚼杏仁组织的颗粒大小和富含脂质的细胞的直径的理论模型来估计破裂的杏仁细胞的脂质释放。我们的结果表明激光衍射是最可靠、最有效的方法。据估计，咀嚼杏仁释放的脂质约占总脂质的 30%，源自破裂组织的破裂细胞。这表明大部分杏仁脂质无法用于消化的早期阶段。进一步的工作将扩展到胃肠道更远端部位的脂质释放和消化研究。这项工作由英国 BBSRC (DRINC; BB/H004866/1) 资助。
Almonds contain phytochemicals and nutrients that potentially have positive health benefits in relation to heart disease, diabetes and obesity. One important mechanism associated with these benefits is the bioaccessibility (release) of lipids from the almond tissue during mastication and digestion. Indeed, it has been reported that in human subjects on almond‐rich diets, a significant proportion of lipid remains undigested, mainly caused by the entrapment of lipid by intact cell walls (dietary fiber). However, the bioaccessibility of almond lipid has not yet been quantified. We have studied this by performing a mastication trial in healthy human volunteers (n = 15). The particle size distribution of chewed almonds was measured using mechanical sieving and laser diffraction methods. Lipid release from ruptured almond cells was estimated using a theoretical model based on the particle size of the chewed almond tissue and the diameter of the lipid‐rich cells. Our results showed that laser diffraction was the most reliable and efficient method. Lipid release from masticated almonds was estimated to be ~30% of total lipid and originated from the ruptured cells of the fractured tissue. This indicates that the majority of almond lipid is unavailable for the early stages of digestion. Further work will extend to studies of lipid release and digestion at more distal sites of the gastrointestinal tract.This work was funded by the BBSRC, UK (DRINC; BB/H004866/1).