Orthostatic hypotension in Parkinson disease A 7-year prospective population-based study

Orthostatic hypotension in Parkinson disease A 7-year prospective population-based study
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帕金森病的直立性低血压一项基于人群的 7 年前瞻性研究

DOI:
10.1212/wnl.0000000000008314
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发表时间:
2019-10-15
期刊:
影响因子:
9.9
通讯作者:
Alves, Guido
Alves, Guido
中科院分区:
医学1区
文献类型:
--
作者:
Hiorth, Ylva Hivand;Pedersen, Kenn Freddy;Alves, Guido

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ObjectiveTo determine the frequency, evolution, and associated features of orthostatic hypotension (OH) over 7 years of prospective follow-up in a population-based, initially drug-naive Parkinson disease (PD) cohort.MethodsWe performed repeated lying and standing blood pressure measurements in 185 patients with newly diagnosed PD and 172 matched normal controls to determine the occurrence of (1) OH using consensus-based criteria and (2) clinically significant OH (mean arterial pressure in standing position