Apocrine Carcinoma, Adenopathies, and Raised TAG‐72 Serum Tumor Marker
Apocrine Carcinoma, Adenopathies, and Raised TAG‐72 Serum Tumor Marker
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顶浆腺癌、腺病和 TAG-72 血清肿瘤标志物升高
DOI：
10.1111/j.1524-4725.2004.30180.x
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发表时间：
2004
影响因子：
2.4
通讯作者：
Jorge Soto De Delas
中科院分区：
文献类型：
--
作者：
J. Santos;J. F. de Quirós;J. S. del Río;M. T. Allende;M. Folgueras;Jorge Soto De Delas
肿瘤相关糖蛋白-72在结肠癌患者血清中的检测已被证明在这些胃肠道腺癌的随访中具有重要意义。结果我们报告一例男性患者表现为右腋窝腺病变。邻近皮肤肿瘤的组织学研究使诊断为皮肤大汗腺癌。在所做的研究中，可以突出显示血清抗体CA72.4的升高。除皮肤肿瘤及腋窝腺病变后，肿瘤标志物均为阴性。结论：据我们所知，这是第一例肿瘤血清标志物与皮肤大汗腺癌相关的病例，这一事实应该在进一步的患者中得到证实。它在监测这种罕见的皮肤肿瘤中的应用也值得注意。
BACKGROUND The detection of tumor-associated glycoprotein-72 in the serum of patients with carcinomas, basically of the colon, has proved to be of great use in the follow-up of these gastrointestinal adenocarcinomas. RESULTS We report the case of a male patient presenting adenopathies in the right axilla. The histologic study of an adjacent skin tumor enabled the diagnosis of a cutaneous apocrine carcinoma. Among the studies made, the increase in the serum antibody CA72.4 can be highlighted. The tumor marker was negative after the extirpation of the skin tumor and the axillary adenopathies. CONCLUSION To our best knowledge, this is the first case in which a tumor serum marker is associated with a cutaneous apocrine carcinoma, a fact that should be confirmed with further patients. Its use in the monitoring of this infrequent skin neoplasia is also noteworthy.