Platinum and Palladium Complexes Containing Cationic Ligands as Catalysts for Arene H/D Exchange and Oxidation
Platinum and Palladium Complexes Containing Cationic Ligands as Catalysts for Arene H/D Exchange and Oxidation
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DOI：
10.1002/anie.201002351
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发表时间：
2010-01-01
影响因子：
16.6
通讯作者：
Sanford, Melanie S.
中科院分区：
文献类型：
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作者：
Emmert, Marion H.;Gary, J. Brannon;Sanford, Melanie S.
CH键的直接官能化经常被认为是有机金属化学的“圣杯”。[1]这种转化的一个开创性的例子是Shilov和他的同事证明，铂(II)盐催化烷烃直接氧化成相应的醇和烷基卤化物。[2]这一领域的后续工作集中于调查这些反应的不同配体，以努力提高反应性和选择性，减缓催化剂分解，并用更具成本效益的替代品取代基于铂(IV)的氧化剂。[3-5]在一项关键的发展中，Catalytica的化学家确定[bpymPtCl2](bpym=联嘧啶)是甲烷在发烟硫酸中氧化成CH3OSO3H的预催化剂
The direct functionalization of CH bonds has frequently been deemed a “Holy Grail” of organometallic chemistry.[1] A seminal example of this transformation was the demonstration by Shilov and co-workers that platinum (II) salts catalyze the direct oxidation of alkanes into their corresponding alcohols and alkyl halides.[2] Subsequent work in this area has focused on surveying diverse ligands for these reactions in an effort to enhance reactivity and selectivity, slow catalyst decomposition, and replace platinum (IV)-based oxidants with more cost-effective alternatives.[3–5] In a key development, chemists at Catalytica identified [bpymPtCl2](bpym= bipyrimidine) as a pre-catalyst for the oxidation of CH4 into CH3OSO3H in fuming H2SO4