Risk factors for postpartum depression in women undergoing elective cesarean section: A prospective cohort study.

Risk factors for postpartum depression in women undergoing elective cesarean section: A prospective cohort study.
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DOI:
10.3389/fmed.2022.1001855
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发表时间:
2022
影响因子:
3.9
通讯作者:
Xu, Zhendong
Xu, Zhendong
中科院分区:
医学3区
文献类型:
--
作者:
Lin, Rong;Lu, Yan;Luo, Wei;Zhang, Bing;Liu, Zhiqiang;Xu, Zhendong

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产后抑郁症(PPD)对母婴健康产生不利影响。剖宫产 (CS) 被认为与 PPD 相关,但没有研究检查接受剖腹产的女性发生 PPD 的危险因素。因此,本研究旨在调查这种关联。 2020 年 12 月至 2021 年 9 月期间进行了一项前瞻性观察研究。共有 590 名接受选择性 CS 的女性参与了这项研究。在妊娠第 32 周、产后 2 天和产后 6 周这三个时间点,通过面对面访谈的方式收集问卷数据。 PPD 的定义是产后 6 周爱丁堡产后抑郁量表 (EPDS) 评分≥ 11。进行多变量逻辑回归分析以确定 PPD 的危险因素。在 590 名女性中,25.4% 患有产后抑郁症 (142/590)。调整混杂因素后,产前焦虑自评量表得分较高(OR = 1.10,95% CI = 1.04–1.16)、产后 2 天出现 PPD 症状(EPDS ≥ 11)(OR = 6.17,95% CI = 1.35–28.31)以及产后 6 周疼痛(OR = 2.14,95% CI = 1.24–3.69)与 PPD 独立相关。产前焦虑、术后早期出现的 PPD 症状以及产后 6 周的疼痛可能与接受 CS 的女性发生 PPD 的风险增加有关。
Postpartum depression (PPD) has adverse effects on maternal and child health. Cesarean section (CS) is suggested to be associated with PPD, but no study has examined the risk factors for PPD in women who underwent CS. Therefore, this study aimed to investigate this association. A prospective observational study was conducted between December 2020 and September 2021. In total, 590 women who underwent elective CS participated in this study. Data were collected using a questionnaire through a face-to-face interview at three time points: 32nd week of gestation, 2 days postpartum, and 6 weeks postpartum. PPD was defined by an Edinburgh Postnatal Depression Scale (EPDS) score of ≥ 11 at 6 weeks postpartum. Multivariate logistic regression analysis was performed to identify the risk factors for PPD. Among the 590 women, 25.4% had PPD (142/590). After adjustment for the confounding factors, high antenatal self-rating anxiety scale score (OR = 1.10, 95% CI = 1.04–1.16), PPD symptoms (EPDS ≥ 11) at 2 days postpartum (OR = 6.17, 95% CI = 1.35–28.31), and pain at 6 weeks postpartum (OR = 2.14, 95% CI = 1.24–3.69) were independently associated with PPD. Prenatal anxiety, PPD symptoms occurring at an early postoperative stage, and pain at 6 weeks postpartum may be associated with an increased risk of PPD among women who undergo CS.
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