Worldwide epidemiology of HBV infection, disease burden, and vaccine prevention
Worldwide epidemiology of HBV infection, disease burden, and vaccine prevention
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DOI：
10.1016/s1386-6532(05)00384-7
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发表时间：
2005-12-01
影响因子：
8.8
通讯作者：
Lavanchy, D.
中科院分区：
文献类型：
--
作者：
Lavanchy, D.
在世界范围内，乙肝病毒是引起人类慢性肝脏反射的肝炎病毒中最常见的，它代表着一个全球性的公共卫生问题。由乙肝病毒引起的慢性肝炎是世界范围内肝细胞癌的主要原因，因此仍然是全球主要的公共卫生问题。这一事实既与频繁出现新的反射的持续发生有关，也与存在大量慢性感染者有关，这可能会发展为慢性肝病的严重和致命的并发症。乙肝及其引起的所有并发症，以及丁型肝炎(HDV)及其并发症，都可以通过接种乙肝疫苗在全球范围内预防，因此，消除乙肝传播和新的急性和慢性感染是一个可行的目标。(C)2005 Elsevier B.V.保留所有权利。
Worldwide, hepatitis B virus (HBV) is the most common among those hepatitis viruses that cause chronic refections of the liver in humans, and it represents a global public health problem. Chronic hepatitis caused by HBV is the major cause of hepatocellulax carcinoma (HCC) worldwide, and remains therefore a major public health problem globally. This fact is related to both the continuing occurrence of frequent new refections and to the presence of a large reservoir of persons chronically infected, which may develop severe and fatal complications of chronic liver disease. Hepatitis B and all of the complications resulting from it, as well hepatitis D (HDV) and its complications, are globally preventable by hepatitis B vaccination, and therefore elimination of HBV transmission and of new acute and chronic infections is a feasible goal. (C) 2005 Elsevier B.V. All rights reserved.