Exploiting anthracene photodimerization within peptides: light induced sequence-selective DNA binding
Exploiting anthracene photodimerization within peptides: light induced sequence-selective DNA binding
复制标题
DOI：
10.1039/c5cc01618e
复制
发表时间：
2015-01-01
影响因子：
4.9
通讯作者：
Peacock, Anna F. A.
中科院分区：
文献类型：
--
作者：
Bullen, Gemma A.;Tucker, James H. R.;Peacock, Anna F. A.
蒽光二聚化在蛋白质或肽系统内的前所未有的使用是通过将其掺入衍生自GCN 4转录因子的DNA结合肽来探索的。这项研究证明了光反应和肽-DNA组装之间的有效和动态的相互作用，每个过程都能够控制其他过程。
The unprecedented use of anthracene photodimerization within a protein or peptide system is explored through its incorporation into a DNA-binding peptide, derived from the GCN4 transcription factor. This study demonstrates an effective and dynamic interplay between a photoreaction and a peptide-DNA assembly, with each process able to exert control over the other.