Low-Grade Esthesioneuroblastoma Presenting as SIADH: A Review of Atypical Manifestations
Low-Grade Esthesioneuroblastoma Presenting as SIADH: A Review of Atypical Manifestations
复制标题
表现为 SIADH 的低度恶性视神经母细胞瘤：非典型表现的回顾
作者：
A. Senchak;J. Freeman;D. Ruhl;Jordan Senchak;C. Klem
摘要鼻中神经母细胞瘤是一种神经内分泌肿瘤，主要表现为鼻腔上段的晚期恶性肿瘤。标志性症状包括鼻塞和鼻出血，这是由局部组织侵犯引起的。在诊断和治疗ENB时，也可能出现不典型的临床特征，必须加以考虑。这些可能包括起源于异位、不寻常的表现症状和相关的副肿瘤综合征。本文报告一例发生于年轻女性的鼻腔ENB，其临床特征不典型。她的肿瘤是低级别的，似乎主要发生在中鼻腔，表现为抗利尿激素不当综合征(SIADH)。她在确诊后不久就怀孕了，这对她的手术处理有影响。我们回顾了不常见的ENB的非典型特征，以及由这些不寻常的特征引起的临床考虑。
Esthesioneuroblastoma (ENB) is a neuroendocrine tumor that typically manifests as advanced stage malignancy in the superior nasal cavity. The hallmark symptoms include nasal obstruction and epistaxis, which result from local tissue invasion. Atypical clinical features can also arise and must be considered when diagnosing and treating ENB. These can include origin in an ectopic location, unusual presenting symptoms, and associated paraneoplastic syndromes. The case described here reports a nasal cavity ENB with atypical clinical features that occurred in a young female. Her tumor was low grade, appeared to arise primarily from the middle nasal cavity, and presented as syndrome of inappropriate antidiuretic hormone (SIADH). She also became pregnant shortly after diagnosis, which had implications on her surgical management. We review the atypical features that uncommonly occur with ENB and the clinical considerations that arise from these unusual characteristics.
由感觉神经母细胞瘤引起的异位库欣综合征。
DOI：
10.4158/ep.10.2.119
发表时间：
2004
期刊：
Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists
影响因子：
--
作者：
Yu,Juan;Koch,ChristianA;Patsalides,Athos;Chang,Richard;Altemus,RosemaryM;Nieman,LynetteK;Pacak,Karel
通讯作者：
Pacak,Karel