Serum omentin-1 levels are inversely associated with the presence and severity of coronary artery disease in patients with metabolic syndrome
Serum omentin-1 levels are inversely associated with the presence and severity of coronary artery disease in patients with metabolic syndrome
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DOI：
10.3109/1354750x.2011.622789
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发表时间：
2011-12-01
期刊：
影响因子：
2.6
通讯作者：
Zhao, Lian-You
中科院分区：
文献类型：
--
作者：
Shang, Fu-Jun;Wang, Jie-Pin;Zhao, Lian-You
内容：Omentin-1是一种由内脏脂肪组织分泌的脂肪因子，与冠状动脉疾病（Coronary Artery Disease，CAD）和代谢紊乱有关。目的：探讨代谢综合征（MetS）患者血清Omentin-1水平与CAD的关系。结果如下：结论：血清omentin-1可能是预测代谢综合征患者CAD发生、发展的潜在生物标志物。
Context: Omentin-1, an adipokine secreted from visceral adipose tissue, has been reported to be associated with coronary artery disease (CAD) and metabolic disorders.Objective: To clarify the relationship between serum omentin-1 levels and the presence and severity of CAD in patients with metabolic syndrome (MetS).Methods: We measured serum omentin-1 levels in 175 consecutive patients with MetS and in 46 controls. Results: Serum omentin-1 levels are inversely associated with the presence and angiographic severity of CAD in MetS patients.Conclusions: Serum omentin-1 might be a potential biomarker to predict the development and progression of CAD in MetS patients.