Effects of Integrated Brain, Body, and Social (IBBS) intervention on ERP measures of attentional control in children with ADHD.
Effects of Integrated Brain, Body, and Social (IBBS) intervention on ERP measures of attentional control in children with ADHD.
复制标题
脑、身体和社会综合 (IBBS) 干预对 ADHD 儿童注意力控制 ERP 测量的影响。
DOI：
10.1016/j.psychres.2019.06.021
复制
发表时间：
2019
影响因子：
11.3
通讯作者：
Sukhodolsky,DenisG
中科院分区：
文献类型：
--
作者：
Smith,StephanieD;Crowley,MichaelJ;Ferrey,Anne;Ramsey,Kathleen;Wexler,BruceE;Leckman,JamesF;Sukhodolsky,DenisG
本研究的主要目的是研究脑、身体和社会综合干预（IBBS）（包括计算机认知训练、体育锻炼和行为管理的多方面治疗）对ADHD儿童注意力控制（P3和N2）ERP的影响。第二个目标是测试ADHD儿童和非ADHD儿童在ERP和Go/No-Go行为测量方面的差异。从IBBS疗效研究中招募的共29名参与者（法师= 7.14岁; 52%男性; 41.4%白色）在治疗前后完成了Go/No-Go任务，同时使用EEG记录了大脑活动。34名匹配的健康对照（HC）在单个时间点完成相同的EEG程序。治疗后，IBBS组的Go P3潜伏期显著早于TAU组。未发现对任何行为指标的治疗效应。治疗前ADHD组与HC组N2差值波差异有统计学意义。患有ADHD的儿童在行为测量上也表现出反应时间较慢。虽然这项初步研究没有显示出强大的治疗效果，但它表明IBBS可能会防止大脑中注意力系统的恶化，并且需要进行更大规模的研究以进行复制。
A primary goal of this study was to examine the impact of an Integrated Brain, Body, and Social (IBBS) intervention (multi-faceted treatment consisting of computerized cognitive training, physical exercise, and behavior management) on ERPs of attentional control (P3 & N2) in children with ADHD. The secondary goal was to test the differences between children with and without ADHD on ERP and Go/No-Go behavioral measures. A total of twenty-nine participants (Mage = 7.14 years; 52% male; 41.4% white) recruited from the IBBS efficacy study comparing IBBS to Treatment-As-Usual (TAU) completed a Go/No-Go task before and after treatment as brain activity was recorded using EEG. Thirty-four matched healthy controls (HC) completed the same EEG procedures at a single time point. Following treatment, the Go P3 latency was significantly earlier for the IBBS group relative to the TAU group. No treatment effects were found on any behavioral measures. Prior to treatment, there was a significant difference between the ADHD group and HC group for the N2 difference wave. Children with ADHD also showed slower reaction times on behavioral measures. Although this pilot study did not reveal robust treatment effects, it suggests that IBBS may prevent the worsening of attentional systems in the brain and larger studies are needed for replication purposes.