Three Cases of Idiopathic Sterile Pyogranulomatous Inflammation of Epidural Fat in Miniature Dachshunds
Three Cases of Idiopathic Sterile Pyogranulomatous Inflammation of Epidural Fat in Miniature Dachshunds
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DOI：
10.1292/jvms.12-0028
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发表时间：
2012-08-01
影响因子：
1.2
通讯作者：
Nakayama, Masanari
中科院分区：
文献类型：
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作者：
Nishida, Hidetaka;Tanaka, Hiroshi;Nakayama, Masanari
三只小型腊肠的进行性共济失调和瘫痪被发现是由T5和L4之间的硬膜外脂肪的特发性不育化脓性肉芽肿性炎症引起的。所有犬均行半椎板切除、硬膜外受压物摘除。硬膜外化脓性肉芽肿性炎症的诊断需要手术发现和组织病理学评估。一只狗在手术后没有恢复运动和传感器功能。有两只狗在手术后神经功能得到了改善，但它们又复发了。口服环孢素治疗对长期缓解有效。特发性不孕性硬膜外脂肪化脓性肉芽肿性炎症可被认为是狗胸腰段脊髓病的原因之一。
Progressive ataxia and paralysis in three Miniature Dachshunds were found to be caused by idiopathic sterile pyogranulomatous inflammation of epidural fat between T5 and L4. All dogs were managed by hemilaminectomy and removal of epidural compressive material. Surgical findings and histopathological evaluation were necessary to diagnose epidural pyogranulomatous inflammation. A dog did not regain motor and sensor function after the surgery. Two dogs had exhibited improved neurological function after the surgery, but they recurred. Oral cyclosporine treatment was useful for their long remission. Idiopathic sterile pyogranulomatous inflammation of epidural fat can be considered to be a cause of thoracolumbar myelopathy in dogs.