Intact attentional control of working memory encoding in schizophrenia
Intact attentional control of working memory encoding in schizophrenia
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DOI：
10.1037/0021-843x.115.4.658
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发表时间：
2006-11-01
影响因子：
4.6
通讯作者：
Luck, Steven J.
中科院分区：
文献类型：
--
作者：
Gold, James M.;Fuller, Rebecca L.;Luck, Steven J.
这项研究报告了精神分裂症(SC)患者对视觉工作记忆(WM)存储的完整注意选择的证据。对62名有SC的参与者和55名没有SC的对照组参与者进行了一系列5个实验的研究，考察了使用自上而下和自下而上的线索来指导工作记忆编码的能力，以及自发选择表征子集进行存储的能力。在所有5个实验中，患有SC的参与者都表现出了一致和强大的能力，可以使用选择性注意来控制WM，这表明了一个显著的保留功能孤岛，因为在SC的参与者中，注意力和WM的损害已经被广泛报道。这些发现表明，在SC中，注意力并没有受到全球性的损害，这使得更准确地描述这种障碍中特定注意力损害的性质成为可能。
This study reports evidence that individuals with schizophrenia (SC) demonstrate intact attentional selection for visual working memory (WM) storage. A group of 62 participants with SC and 55 control participants without SC were studied in a series of 5 experiments that examined the ability to use top-down and bottom-up cues to guide WM encoding, as well as the ability to spontaneously select a subset of representations for storage. Participants with SC exhibited a consistent and robust ability to use selective attention in the control of WM in all 5 experiments, demonstrating a remarkable island of preserved functioning given the broad spectrum of impairments of attention and WM that have been widely reported in those with SC. These findings indicate that attention is not globally impaired in SC and make it possible to delineate more precisely the nature of the specific impairment of attention in this disorder.