Cognitive tuning of corticospinal excitability during human gait: adaptation to the phase
Cognitive tuning of corticospinal excitability during human gait: adaptation to the phase
复制标题
人类步态期间皮质脊髓兴奋性的认知调节：阶段适应
DOI：
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发表时间：
2004
期刊：
影响因子：
--
通讯作者：
M. Bonnard
中科院分区：
文献类型：
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作者：
M. Camus;J. Pailhous;M. Bonnard
本研究的目的是研究在人类步态过程中，皮质脊髓（CS）兴奋性的认知调节如何适应诱发运动的类型（伸展与伸展）。经颅磁刺激（TMS）既被用作引起运动的中枢扰动，又被用作量化研究中肌肉（RF/BF）CS兴奋性的工具。在第一种情况下（Dst），TMS发生在站立中期，诱导髋关节伸展，而在第二种情况下（Dsw），TMS发生在摆动阶段开始时，诱导髋关节屈曲。在这两种情况下，要求受试者在认知上准备不干预（NINT）或补偿（COMP）诱发运动。结果表明，无论诱发运动的类型如何，准备补偿都会导致参与抵消可能的中枢扰动的肌肉的CS兴奋性选择性增加，即髋伸肌（BF）在摆动阶段补偿诱发屈曲或髋屈肌（RF）在站立阶段补偿诱发伸展。后者的结果提供了第一个证据的调制CS兴奋性的近端肌肉在站立阶段。总之，CS兴奋性的认知调谐被发现适应步态相位。此外，相同的选择性准备策略，观察是否中央扰动发生在立场或摆动阶段的步骤周期。
The aim of this study was to investigate how the cognitive tuning of corticospinal (CS) excitability adapts to the type of evoked‐movement (Flexion vs. Extension) during human gait. Transcranial magnetic stimulation (TMS) was used both as a central perturbation evoking a movement and as a tool for quantifying the CS excitability of the muscles under study (RF/BF). In the first condition (Dst), the TMS occurred at mid‐stance, inducing hip extension, whereas in the second condition (Dsw), the TMS occurred at the beginning of the swing phase, inducing hip flexion. In both conditions, the subjects were asked to cognitively prepare to either not intervene (NINT) or to compensate (COMP) for the evoked‐movements. The results showed that, regardless of the type of evoked‐movement, preparing to compensate resulted in a selective increase in the CS excitability to those muscles that would be involved in counteracting the possible central perturbation, i.e. the hip extensor muscle (BF) to compensate for an evoked flexion during the swing phase or the hip flexor muscle (RF) to compensate for an evoked extension during the stance phase. This latter result offers the first evidence of a modulation in CS excitability to the proximal muscles during the stance phase. In conclusion, the cognitive tuning of CS excitability was found to adapt to the gait phases. Moreover, the same selective preparation strategy was observed whether the central perturbation occurred during the stance or the swing phase of the step cycle.
负性运动想象期间皮质脊髓兴奋性的抑制。
影响因子：
2.5
作者：
Sohn,YoungH;Dang,Nguyet;Hallett,Mark
通讯作者：
Hallett,Mark