Development of pulmonary blood flow evaluation method with a dynamic flat-panel detector: quantitative correlation analysis with findings on perfusion scan
Development of pulmonary blood flow evaluation method with a dynamic flat-panel detector: quantitative correlation analysis with findings on perfusion scan
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DOI：
10.1007/s12194-009-0074-1
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发表时间：
2010-01-01
影响因子：
1.6
通讯作者：
Matsui, Osamu
中科院分区：
文献类型：
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作者：
Tanaka, Rie;Sanada, Shigeru;Matsui, Osamu
肺血流量在动态胸片中反映为X射线透明度的变化，即，像素值。因此，血流量减少应被视为X射线透射率变化的减少。我们进行了本研究，以探讨肺血流评价与动态平板探测器（FPD）的可行性。采用动态FPD系统对14例受试者进行连续胸片检查。测量每个局部区域中像素值的变化，并通过使用灰度级将其映射到原始图像上，其中小变化和大变化分别以白色和黑色显示。将所得图像与灌注扫描中的结果进行比较。计算了各局部区域像素值变化与放射性计数变化的互相关系数。在所有患者中，肺血流障碍表示为标测图像上像素值变化的减少，并且观察到像素值变化的分布与放射性计数变化的分布之间的相关性（0.7
Pulmonary blood flow is reflected in dynamic chest radiographs as changes in X-ray translucency, i.e., pixel values. Thus, decreased blood flow should be observed as a reduction of the variation of X-ray translucency. We performed the present study to investigate the feasibility of pulmonary blood flow evaluation with a dynamic flat-panel detector (FPD). Sequential chest radiographs of 14 subjects were obtained with a dynamic FPD system. The changes in pixel value in each local area were measured and mapped on the original image by use of a gray scale in which small and large changes were shown in white and black, respectively. The resulting images were compared to the findings in perfusion scans. The cross-correlation coefficients of the changes in pixel value and radioactivity counts in each local area were also computed. In all patients, pulmonary blood flow disorder was indicated as a reduction of changes in pixel values on the mapping image, and a correlation was observed between the distribution of changes in pixel value and those in radioactivity counts (0.7