Validation of the SarQoL®, a specific health-related quality of life questionnaire for Sarcopenia
Validation of the SarQoL®, a specific health-related quality of life questionnaire for Sarcopenia
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DOI：
10.1002/jcsm.12149
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发表时间：
2017-04-01
影响因子：
8.9
通讯作者：
Bruyere, Olivier
中科院分区：
文献类型：
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作者：
Beaudart, Charlotte;Biver, Emmanuel;Bruyere, Olivier
背景：一种特殊的自我管理的健康相关的生活质量问卷，肌肉减少症和生活质量（SarQoL（R）），最近已经开发出来。该问卷由55个项目组成，转化为22个问题，并分为七个生活质量领域。目前的工作的目的是评估的心理测量特性（辨别力，有效性，可靠性，地板和天花板的影响）的SarQoL（R）questionnaire.Methods Sarcophytic主题被招募在门诊诊所在列日，比利时和诊断根据欧洲工作组制定的算法在老年人肌肉减少症。在调整潜在的混杂变量后，我们使用逻辑回归比较了肌肉减少症和非肌肉减少症受试者之间的SarQoL（R）评分。内部一致性的信度，采用克朗巴赫的α系数，结构效度进行了评估，使用收敛和发散效度。两周后，使用组内相关系数（ICC）进行重测信度验证。结果296名受试者中位年龄为73.3（68.9-78.6）岁。其中43人被诊断为肌肉减少症。调整潜在混杂因素后，肌减少症受试者的SarQoL（R）问卷总分和不同维度的评分显著低于非肌减少症受试者（肌减少症受试者为54.7（45.9-66.3）vs非肌减少症受试者为67.8（57.3 - 79.0），OR 0.93（95%CI 0.90-0.96））。关于内部一致性，Cronbach的α系数为0.87。SarQoL（R）问卷数据显示与简明健康调查表36（SF-36）和EuroQoL 5维（EQ-5D）问卷的某些领域以及活动性测试具有良好的相关性。试验和复检之间的一致性极佳，ICC为0.91（95% CI 0.82-0.95）。最后，无论是地板还是天花板的影响被detected.Conclusions SarQoL（R）问卷是有效的，一致的，可靠的，因此可以推荐用于临床和研究目的。然而，其变化的敏感性需要在未来的纵向研究中进行评估。
Background A specific self-administrated health-related quality of life questionnaire for sarcopenia, the Sarcopenia and Quality Of Life (SarQoL (R)), has been recently developed. This questionnaire is composed of 55 items translated into 22 questions and organized into seven domains of quality of life. The objective of the present work is to evaluate the psychometric properties (discriminative power, validity, reliability, floor and ceiling effects) of the SarQoL (R) questionnaire.Methods Sarcopenic subjects were recruited in an outpatient clinic in Liege, Belgium and were diagnosed according to the algorithm developed by the European Working Group on Sarcopenia in Older People. We compared the score of the SarQoL (R) between sarcopenic and non-sarcopenic subjects using a logistic regression after adjustment for potential confounding variables. Internal consistency reliability was determined using Cronbach's alpha coefficient; construct validity was assessed using convergent and divergent validities. Test-retest reliability was verified after a two-week interval using the intra-class correlation coefficient (ICC). At last, floor and ceiling effects were also tested.Results A total of 296 subjects with a median age of 73.3 (68.9-78.6) years were recruited for this study. Among them, 43 were diagnosed sarcopenic. After adjustment for potential confounding factors, the total score and the scores of the different dimensions of the SarQoL (R) questionnaire were significantly lower for sarcopenic than for non-sarcopenic subjects (54.7 (45.9-66.3) for sarcopenic vs. 67.8 (57.3 - 79.0) for non sarcopenic, OR 0.93 (95%CI 0.90-0.96)). Regarding internal consistency, the Cronbach's alpha coefficient was 0.87. The SarQoL (R) questionnaire data showed good correlation with some domains of the Short-Form 36 (SF-36) and the EuroQoL 5-dimension (EQ-5D) questionnaires and with the mobility test. An excellent agreement between the test and the retest was found with an ICC of 0.91 (95% CI 0.82-0.95). At last, neither floor nor ceiling effects were detected.Conclusions The SarQoL (R) questionnaire is valid, consistent, and reliable and can therefore be recommended for clinical and research purposes. However, its sensitivity to change needs to be assessed in future longitudinal studies.