Surface-Enhanced Raman Spectroscopy (SERS) for Environmental Analyses
Surface-Enhanced Raman Spectroscopy (SERS) for Environmental Analyses
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DOI：
10.1021/es101228z
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发表时间：
2010-10-15
影响因子：
11.4
通讯作者：
Vikesland, Peter J.
中科院分区：
文献类型：
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作者：
Halvorson, Rebecca A.;Vikesland, Peter J.
尽管为保护公众健康作出了广泛努力，但当有毒化学品和微生物威胁逃避检测时，疾病暴发仍会发生。被大肠杆菌0157：117污染的花生酱和农产品、威斯康星州密尔沃基和安大略省沃克顿（加拿大）被隐孢子虫污染的饮用水、被蓝藻毒素污染的地表沃茨以及带有炭疽孢子的邮件，每一个都代表了一种爆发，这种爆发可能已经被更快和更容易获得的病原体或化学检测方法所预防。尽管存在多种用于在各种基质中检测污染物的技术，但监测每种分析物类别通常需要特定的仪器。然而，今天，人们越来越兴奋的潜在用途的表面增强拉曼光谱（Sers）的同时多重检测的传染性和非传染性污染物在一系列的环境。正如目前所设想的，Sers是一个平台，用于简单，快速，廉价，可靠和强大的方法来同时筛选单一或多个污染物类别（1-4）。数以千计的Sers出版物记录了在实现这一愿景方面取得的重大进展;然而，如本文所述，要实现这些目标，必须克服几个可以克服的障碍。
Despite extensive efforts to protect public health, disease outbreaks still occur when toxic chemicals and microbial threats evade detection. Peanut butter and produce tainted with Escherichia coli 0157:117, drinking water in Milwaukee, WI and Walkerton, ON (Canada) polluted by Cryptosporidium, surface waters contaminated by cyanotoxins, and mail laced with anthrax spores each represent an outbreak that may have been prevented with faster and more readily available pathogen or chemical detection methods. Although numerous techniques for contaminant detection in a variety of matrices exist, monitoring each analyte class generally requires specific instrumentation. Today, however, there is growing excitement about the potential use of surface-enhanced Raman spectroscopy (SERS) for simultaneous multiplex detection of infectious and noninfectious contaminants in a range of environmental milieu. As currently envisioned, SERS is a platform for simple, fast, inexpensive, reliable, and robust methods to screen single or multiple contaminant classes simultaneously (1-4). Thousands of SERS publications document significant progress in achieving such a vision; however, as outlined herein several surmountable obstacles must be overcome to achieve these goals.