Sonochemical Coatings of ZnO and CuO Nanoparticles Inhibit Streptococcus mutans Biofilm Formation on Teeth Model
Sonochemical Coatings of ZnO and CuO Nanoparticles Inhibit Streptococcus mutans Biofilm Formation on Teeth Model
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DOI：
10.1021/la301432a
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发表时间：
2012-08-21
期刊：
影响因子：
3.9
通讯作者：
Banin, Ehud
中科院分区：
文献类型：
--
作者：
Eshed, Michal;Lellouche, Jonathan;Banin, Ehud
抗生素耐药性促使人们寻找能够抑制细菌生长的新药物。我们最近报道了使用声化学辐射合成的纳米级 ZnO 和 CuO 纳米颗粒 (NP) 的抗生物膜活性。在这项研究中，我们检查了粉末形式的 ZnO 和 CuO NP 的抗菌活性，并使用声化学检查了涂有 ZnO 和 CuO NP 的牙齿表面的抗菌膜行为。游离 ZnO 和 CuO NPs 抑制变形链球菌生物膜的形成。此外，通过使用声化学程序，我们能够在牙齿表面涂覆抑制细菌定植的涂层。
Antibiotic resistance has prompted the search for new agents that can inhibit bacterial growth. We recently reported on the antibiofilm activities of nanosized ZnO and CuO nanoparticles (NPs) synthesized by using sonochemical irradiation. In this study, we examined the antibacterial activity of ZnO and CuO NPs in a powder form and also examined the antibiofilm behavior of teeth surfaces that were coated with ZnO and CuO NPs using sonochemistry. Free ZnO and CuO NPs inhibited biofilm formation of Streptococcus mutans. Furthermore, by using the sonochemical procedure, we were able to coat teeth surfaces that inhibited bacterial colonization.