Bronchoconstrictor Action of Bradykinin, Kallidin and Eledoisin
Bronchoconstrictor Action of Bradykinin, Kallidin and Eledoisin
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缓激肽、激肽和 Eledoisin 的支气管收缩作用
作者：
H. Collier
Gjurin和Westermann关于缓激肽对豚鼠气管支气管肌的作用不同于5-羟色胺的有趣观察与以前的发现一致。例如，Jänkälä和Virtama 1从放射照相术中得出结论，5-羟色胺“引起豚鼠所有可收缩支气管树的剧烈收缩”，而“缓激肽显然只影响呼吸性细支气管”。我很高兴Gjurin和Westermann支持我们之前提出的观点，缓激肽也可能影响肺胸膜表面的平滑肌。
THE interesting observation of Gjuriš and Westermann that bradykinin differs from 5-hydroxytryptamine in its action on the tracheobronchial muscle of the guinea-pig accords with previous findings. For example, Jänkälä and Virtama1 concluded from radiography that 5-hydroxytryptamine “causes vigorous constriction of all the constrictable bronchial tree of the guinea-pig”, whereas “bradykinin apparently only affects the respiratory bronchioles”. I am glad that Gjuriš and Westermann support the suggestion we made some tune ago2, that bradykinin may also affect the smooth muscles of the pleural surface of the lung.