Targeting HIV-related outcomes with intravenous drug users maintained on methadone: A randomized clinical trial of a harm reduction group therapy
Targeting HIV-related outcomes with intravenous drug users maintained on methadone: A randomized clinical trial of a harm reduction group therapy
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DOI：
10.1016/s0740-5472(03)00159-4
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发表时间：
2004-03-01
影响因子：
3.9
通讯作者：
Doebrick, C
中科院分区：
文献类型：
--
作者：
Avants, SK;Margolin, A;Doebrick, C
考虑到适当的辅助治疗类型和水平，美沙酮维持计划(MMPs)有可能在降低艾滋病毒风险方面发挥重要作用。在这项研究中，我们基于行为改变的信息-动机-行为技能模型，对注射吸毒者进行了为期12次的减少伤害团体干预的有效性，重点是降低毒品和性风险。220名接受治疗的患者被随机分成两组，一组接受标准护理(SC)--每月2小时的咨询和单次降低风险干预--另一组接受SC加减少伤害组(HRG)。结果显示，在治疗期间，接受HRG的患者更有可能戒除可卡因，报告的不安全性行为较少。治疗后，HRG患者在性风险测试中得分更高，并报告在高危性情况下提高了自我效能。通过每周一次的减害小组治疗来加强美沙酮的维持有点昂贵，但可以带来与艾滋病毒传播有关的行为和态度的积极变化。(C)2004 Elsevier Inc.保留所有权利。
Methadone maintenance programs (MMP) have the potential to play an important role in reducing HIV risk, given the appropriate type and level of ancillary treatments. In this study, we investigated the efficacy of a 12-session harm reduction group intervention for injection drug users, based upon the Information-Motivation-Behavioral skills model of behavior change, that focused on reducing both drug and sex risk. Two hundred and twenty patients entering an MMP were randomized to receive either standard care (SC)-2 hours of counseling per month and a single-session risk reduction intervention-or SC plus the harm reduction group (HRG). Results showed that during treatment, patients receiving HRG were more likely to be abstinent from cocaine and to report fewer unsafe sexual practices. Post-treatment, HRG patients scored higher on a sexual risk quiz and reported increased self-efficacy in high risk sexual situations. Enhancing methadone maintenance with a weekly harm reduction group treatment was somewhat more expensive but can bring about positive changes in behaviors and attitudes that are associated with the transmission of HIV. (C) 2004 Elsevier Inc. All rights reserved.