THE EFFECT OF TREATMENT ON ACTINOBACILLUS-ACTINOMYCETEMCOMITANS IN LOCALIZED JUVENILE PERIODONTITIS
THE EFFECT OF TREATMENT ON ACTINOBACILLUS-ACTINOMYCETEMCOMITANS IN LOCALIZED JUVENILE PERIODONTITIS
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DOI：
10.1902/jop.1986.57.2.94
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发表时间：
1986-02-01
影响因子：
4.3
通讯作者：
SOCRANSKY, SS
中科院分区：
文献类型：
--
作者：
MANDELL, RL;TRIPODI, LS;SOCRANSKY, SS
三种治疗方案，包括局部四环素交付，全身多西环素和手术加全身多西环素在局部青少年牙周炎（LJP）的人口进行了调查。在所研究的治疗中，只有手术加全身性强力霉素14天可有效消除或抑制伴放线放线杆菌（一种与LJP病变密切相关的生物体）。虽然手术加抗生素是上级治疗方法，但似乎存在再次感染或不完全消除微生物的可能性。仔细的长期随访，包括临床和微生物监测，强烈建议在这个牙周人口。
Three treatment regimens including local tetracycline delivery, systemic doxycycline and surgery plus systemic doxycycline were investigated in a localized juvenile periodontitis (LJP) population. Of the investigated treatments only surgery plus systemic doxycycline for 14 days was effective in eliminating or suppressing Actinobacillus actinomycetemcomitans, an organism strongly associated with LJP lesions. While surgery plus antibiotics was the superior treatment, it appears that the possibility of reinfection or incomplete elimination of the organism exists. Careful long-term follow-up, including clinical and microbiological monitoring, is highly recommended in this periodontal population.