Predicting the probability of conception in dairy cows with clinical endometritis based on a combination of anamnestic information and examination results
Predicting the probability of conception in dairy cows with clinical endometritis based on a combination of anamnestic information and examination results
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DOI：
10.1016/j.theriogenology.2019.07.004
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发表时间：
2019-10-15
期刊：
影响因子：
2.8
通讯作者：
Bollwein, H.
中科院分区：
文献类型：
--
作者：
Ernstberger, M.;Oehl, H.;Bollwein, H.
本研究的目的是通过综合检测结果，提高对临床子宫内膜炎奶牛受孕概率的预测。为此，总共对1386头奶牛进行了临床子宫内膜炎筛查，收集了286头奶牛的数据，包括产犊史、产褥期或合并疾病以及奶牛特有的数据(品种、产次、产后对照1(PC1=22-45天的产奶量(DIM))和日产奶量。临床子宫内膜炎的诊断是在PC1时用Metricheck阴道分泌物评分，评分为1~3(子宫内膜炎评分1~3)。进行了详细的临床和妇科检查，包括外部检查、经直肠触诊和生殖道(宫颈、子宫和卵巢)的超声检查、阴道镜检查和宫内内容物的微生物学分析。临床子宫内膜炎奶牛(286头)按PC1的卵巢检查结果(黄体、优势卵泡)进行治疗。产后21+/-1d进行第二次产后对照。数据收集一直持续到200天。采用卡方检验和二元Logistic回归分析确定ES-3的危险因素及其对ES分布的影响。在条件推理树的基础上，分析了不同DiM(100、150和200 Dim)下大量检查参数对妊娠结局的多变量含义。临床子宫内膜炎患病率为28%。PC1的卵巢发现对生殖性能没有任何影响。研究前的产后疾病、可见的阴道分泌物(WD)和化脓性螺旋体(TP)的存在与ES 3相关。VVD或TP作为决定因素显著地主导着所有暗期的妊娠状态的预测。与没有这些发现的奶牛相比，患有WD或TP的奶牛在所有阴暗的时间都有较低的受孕率，但两组的预测准确性相似。提示WD是一项有实用价值的检测参数，可用于农场妊娠预测。因此，它可能有助于在农场条件下患有临床子宫内膜炎的奶牛的早期繁殖决策。(C)2019年由Elsevier Inc.出版。
The objective of this study was to improve prediction of the probability of conception in dairy cows with clinical endometritis by means of a combination of examination results. For this purpose, a total of 1386 dairy cows were screened for clinical endometritis and data from 286 cows were collected including the calving history, puerperal or concurrent diseases and cow-specific data (breed, parity, BCS at puerperal control 1 (PC 1 = 22-45 days in milk (DIM)), and daily milk yield). The diagnosis of clinical endometritis was made at PC 1 by vaginal discharge scoring with a Metricheck device on a scale from 1 to 3 (endometritis score (ES) 1 to 3). A detailed clinical and gynecological examination including external inspection, transrectal palpation and ultrasonographic examination of the genital tract (cervix, uterus, and ovaries), vaginoscopy and microbiological analysis of the intrauterine content were performed. All cows with clinical endometritis (n = 286) were treated according to the ovarian findings (corpus luteum, dominant follicle) at PC 1. A second puerperal control was performed 21 +/- 1 days later. Data was collected until 200 DIM. The risk factors for ES 3 and their effect on the distribution of ES were determined by the Chi-square test and binary logistic regression. Multivariable implications of a large sum of examination parameters on the pregnancy outcome at different DIM (100, 150 and 200 DIM) were analyzed on the basis of conditional inference trees. The prevalence of clinical endometritis was 28%. The ovarian findings at PC 1 did not have any impact on reproductive performance. Puerperal diseases prior to the study, visible vaginal discharge (WD) and the presence of Trueperella pyogenes (TP) were associated with an ES 3. The prediction of pregnancy status for all DIM times was dominated significantly by VVD or TP as decisive factors. Cows with WD or TP had lower conception rates at all DIM times than cows without these findings, but the predictive accuracy was similar for both groups. These results suggest that WD is a valuable and practical examination parameter, which can be used for pregnancy prediction on farm. Therefore, it might facilitate early breeding decisions in cows with clinical endometritis under farm conditions. (C) 2019 Published by Elsevier Inc.