π Stacking Effects in Asymmetric Synthesis
π Stacking Effects in Asymmetric Synthesis
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DOI：
10.1055/s-1995-3957
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发表时间：
1995-05
期刊：
影响因子：
--
通讯作者：
Graham B Jones;Brant J. Chapman
中科院分区：
文献类型：
--
作者：
Graham B Jones;Brant J. Chapman
综述了π堆积在不对称合成中的作用和优点。具体而言，手性助剂和手性催化剂实现的不对称诱导可以通过π堆积效应来增强，从而将反应物的一种构型优先锁定在给定的过渡态组装中。将重点介绍此类系统的演变、其在合成中的应用以及分子识别领域的相关发展。
The effects and benefits of π stacking in asymmetric synthesis is reviewed. Specifically, asymmetric induction achieved with chiral auxiliaries and chiral catalysts can be enhanced by π stacking effects, locking one confirmation of a reactant preferentially in a given transition state assembly. The evolution of such systems, their application in synthesis, together with related developments in the field of molecular recognition will be highlighted.