Multicomponent T2 relaxation studies of the avian egg

Multicomponent T2 relaxation studies of the avian egg
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DOI:
10.1002/mrm.25762
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发表时间:
2016-05-01
影响因子:
3.3
通讯作者:
Maier, Stephan E.
Maier, Stephan E.
中科院分区:
医学3区
文献类型:
--
作者:
Mitsouras, Dimitris;Mulkern, Robert V.;Maier, Stephan E.

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PurposeTo调查的组织样多指数T-2信号衰减在avian eggs.MethodsTransverse弛豫研究生,半熟和熟鸡蛋进行了3特斯拉使用三维Carr-Purcell-Meiboom-Gill成像序列。在TE范围为11至354毫秒的信号衰减进行了拟合,假设单和多组分信号衰减与多达三个单独的衰减组件。脂肪饱和度被用来促进所观察到的衰变components.ResultsEgg白色,蛋黄和位于中央latebra的光谱分配都表现出非单指数T-2衰变。具体来说,鸡蛋白色表现出两个组件的衰减与中间和长的T-2时间。与此同时,蛋黄和latebra通常最好的特点与三指数衰减,短,中间和非常长的T-2衰减时间。脂肪饱和度表明,蛋黄的中间成分可能是脂类。烹饪的鸡蛋深刻地改变了衰变curve.ConclusionAvian鸡蛋T-2衰变曲线涵盖了广泛的衰变时间。观察到的T-2成分在蛋黄和latebra短至10毫秒,可能证明有价值的测试临床序列设计来测量短T-2成分,如髓鞘相关的水在大脑中。因此,我们建议鸡蛋可以是一个通用的和广泛使用的MR横向弛豫体模。Magn Reson Med 75:2156-2164,2016。(c)2015年威利期刊公司
PurposeTo investigate the tissue-like multiexponential T-2 signal decays in avian eggs.MethodsTransverse relaxation studies of raw, soft-boiled and hard-boiled eggs were performed at 3 Tesla using a three-dimensional Carr-Purcell-Meiboom-Gill imaging sequence. Signal decays over a TE range of 11 to 354 ms were fitted assuming single- and multicomponent signal decays with up to three separately decaying components. Fat saturation was used to facilitate spectral assignment of observed decay components.ResultsEgg white, yolk and the centrally located latebra all demonstrate nonmonoexponential T-2 decays. Specifically, egg white exhibits two-component decays with intermediate and long T-2 times. Meanwhile, yolk and latebra are generally best characterized with triexponential decays, with short, intermediate and very long T-2 decay times. Fat saturation revealed that the intermediate component of yolk could be attributed to lipids. Cooking of the egg profoundly altered the decay curves.ConclusionAvian egg T-2 decay curves cover a wide range of decay times. Observed T-2 components in yolk and latebra as short as 10 ms, may prove valuable for testing clinical sequences designed to measure short T-2 components, such as myelin-associated water in the brain. Thus we propose that the egg can be a versatile and widely available MR transverse relaxation phantom. Magn Reson Med 75:2156-2164, 2016. (c) 2015 Wiley Periodicals, Inc.