GeneXplorer: an interactive web application for microarray data visualization and analysis

GeneXplorer: an interactive web application for microarray data visualization and analysis
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DOI:
10.1186/1471-2105-5-141
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发表时间:
2004-10-01
期刊:
影响因子:
3
通讯作者:
Sherlock, G
Sherlock, G
中科院分区:
生物学4区
文献类型:
--
作者:
Rees, CA;Demeter, J;Sherlock, G

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背景:在发布大规模微阵列数据集时,创建补充网站是非常有价值的,无论是完整的数据,还是与论文中图形对应的选定子集,都可以浏览。我们着手创建一个CGI应用程序,其中包含一些现有的独立软件的许多功能,用于集群微阵列数据的可视化。结果:我们提出了GeneXplorer,一个在web环境中用于交互式微阵列数据可视化和分析的web应用程序。GeneXplorer允许用户以直观的方式浏览微阵列数据集。它通过Internet提供对微阵列数据的简单访问,并且仅使用HTML和JavaScript来显示图形和注释信息。它提供数据的雷达和缩放视图,允许显示基于Pearson相关性的基因表达向量的最近邻居,并提供搜索基因注释字段的功能。结论:该软件是在宽松的MIT开源许可下发布的,完整的文档和整个源代码可以从CPAN http://search.cpan.org/dist/Microarray-GeneXplorer/免费下载。
Background: When publishing large-scale microarray datasets, it is of great value to create supplemental websites where either the full data, or selected subsets corresponding to figures within the paper, can be browsed. We set out to create a CGI application containing many of the features of some of the existing standalone software for the visualization of clustered microarray data.Results: We present GeneXplorer, a web application for interactive microarray data visualization and analysis in a web environment. GeneXplorer allows users to browse a microarray dataset in an intuitive fashion. It provides simple access to microarray data over the Internet and uses only HTML and JavaScript to display graphic and annotation information. It provides radar and zoom views of the data, allows display of the nearest neighbors to a gene expression vector based on their Pearson correlations and provides the ability to search gene annotation fields.Conclusions: The software is released under the permissive MIT Open Source license, and the complete documentation and the entire source code are freely available for download from CPAN http://search.cpan.org/dist/Microarray-GeneXplorer/.